BACKGROUND & AIMS:
:Pseudoephedrine (PSE) is one of the main ingredients used to manufacture methamphetamine (MA); approximately 700 to 1000 PSE pills are necessary to "cook" a batch of MA. Steps have been taken to decrease the availability of ingredients needed to concoct MA. On May 21, 2005, the state of Iowa enacted a strict law, making PSE a Schedule V Controlled substance, restricting PSE availability, and sales. Using the same 6-month time frames in 2004 and 2005, we retrospectively compared epidemiological data on burn patients in the year before the new PSE law and again immediately after the law was enacted. Data collected between May 21 to December 31, 2004 and 2005 included sex, age, length of stay, body surface area burn, urine drug toxicity status, insurance status, and cost of hospital stay. Reports on statewide MA laboratory incidents were provided by the Office of Drug Control Policy. In 2004, Iowa ranked second in the nation for MA lab incidents, seizing an average of 120 labs per month. In 2006, Iowa ranked eighth in the nation for MA lab incidents, when only 20 labs per month were seized, an 83% decreased from the previous year. By limiting the availability of PSE, Iowa saw a marked decrease in MA laboratory-related incidents, leading to a drastic decrease in MA related burns statewide.
背景与目标:
:伪麻黄碱(PSE)是用于制造甲基苯丙胺(MA)的主要成分之一;大约需要700到1000个PSE药丸来“煮制”一批MA。已经采取措施减少炮制MA所需成分的可用性。 2005年5月21日,爱荷华州制定了严格的法律,将PSE列为附表V受控物质,限制了PSE的供应和销售。使用2004年和2005年相同的6个月时间框架,我们回顾性比较了新《 PSE法》颁布前一年和该法颁布后立即进行的烧伤患者的流行病学数据。在2004年5月21日至12月31日至2005年之间收集的数据包括性别,年龄,住院时间,体表烧伤,尿液药物中毒状态,保险状态和住院费用。药物管制政策办公室提供了有关全州MA实验室事件的报告。 2004年,爱荷华州在MA实验室事件方面名列全美第二,平均每月要夺取120个实验室。 2006年,爱荷华州在MA实验室事件中排名全国第八,每月仅缉获20个实验室,比上一年下降了83%。通过限制PSE的可用性,爱荷华州看到与MA实验室相关的事件明显减少,从而导致全州与MA相关的烧伤急剧减少。