We conducted a study on 152 patients with multiple sclerosis (MS) who were born in North Africa and migrated to France. Information was obtained from patients on common childhood infections. We found that, in most cases, common childhood illnesses occurred before migration, but these infections occurred at later ages when the patients were in France: the mean differences were equal to 3 years for measles, 2.1 years for chickenpox, and 4.5 years for mumps. In comparison with data available for the general populations of Algeria and France, the mean ages of childhood infections, and particularly measles, were higher in MS patients. Data confirm that, wherever they live, MS patients tend to have childhood infections at a relatively late age and suggest that migration delays the age of viral infections. This might be one of the possible explanations for the effect of migration on the risk of MS.

译文

:我们对出生于北非并移居法国的152例多发性硬化症(MS)患者进行了研究。从患者那里获得了有关常见儿童期感染的信息。我们发现,在大多数情况下,常见的儿童疾病发生在迁徙之前,但是这些感染发生在法国患者以后的较晚年龄:麻疹的平均差异等于3岁,水痘的平均差异等于2.1岁,腮腺炎的平均差异等于4.5岁。与可用于阿尔及利亚和法国普通人群的数据相比,MS患者的儿童感染(尤其是麻疹)平均年龄更高。数据证实,无论身在何处,MS患者都倾向于在相对较晚的年龄段感染儿童,这表明迁移会延迟病毒感染的年龄。这可能是迁移对MS风险影响的可能解释之一。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录