Describing clinical outcomes from assisted reproduction technology (ART) treatment cycles has been an evolving challenge throughout the world. Three simple metrics provide a transparent and highly accurate summary of ART outcomes. The first metric is the probability of having no embryos available to transfer. This metric incorporates all causes of failure from initiation of the treatment cycle up to the point immediately before actual embryo transfer. Patients will know what the risk is of failing, whether it is due to poor follicular stimulation, failed fertilization, poor embryo development, or abnormal preimplantation genetic testing for aneuploidy (PGT-A) results. The second and most important metric is sustained implantation rate: the probability that any transferred embryo will implant and progress to delivery. In the event of a single-embryo transfer, the metric is identical to delivery rate per transfer. By calculating per embryo, it provides a summary of the quality of outcomes within the program without the obscuring effect of multiple-embryo transfer. The final metric is the number of supernumerary embryos cryopreserved during the cycle. This speaks to the efficiency of the process by providing an estimate of potential benefits which may come from an additional transfer should the first one be unsuccessful or even to allow the couple to pursue an additional child without another full ART cycle. These metrics are easy to calculate and provide a detailed picture of the outcomes attained by the program.

译文

:描述辅助生殖技术(ART)治疗周期的临床结果一直是世界范围内不断发展的挑战。三个简单的指标可提供ART结果的透明且高度准确的摘要。第一个指标是没有胚胎可转移的概率。该指标涵盖了从治疗周期开始到实际胚胎移植之前的所有失败原因。患者将知道失败的风险是什么,无论是由于不良的卵泡刺激,受精失败,胚胎发育不良还是非整倍性(PGT-A)结果的植入前基因测试异常。第二个也是最重要的指标是持续着床率:任何转移的胚胎将着床并继续进行分娩的概率。如果是单胚胎移植,则该度量标准与每次转移的交付率相同。通过计算每个胚胎,它提供了该程序中结果质量的摘要,而没有多胚胎移植的影响。最终指标是在周期中冷冻保存的多余胚胎的数量。通过提供一个可能的收益的估计,可以证明该过程的效率,如果第一次转移失败或什至允许夫妇在没有另一个完整的抗逆转录病毒治疗周期的情况下继续寻找另一个孩子,可能会从一次额外的转移中获得潜在的利益。这些度量标准易于计算,并提供程序所达到的结果的详细信息。

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