PURPOSE:Vitamin D deficiency is a global health problem that is associated with increased risks of major diseases. This study investigated the status of 25-hydroxyvitamin D [25(OH)D] and its demographic and lifestyle determinants among Korean adults. METHODS:A total of 5,847 adults who had participated in the Korean National Health and Nutrition Examination Survey of 2008 (KNHANES) were included in the present study. Stepwise linear regression analysis was performed to determine the demographic and lifestyle determinants of 25(OH)D concentration. RESULTS:The weighted prevalence (standard error) of 25(OH)D deficiency (<20 ng/mL) was 49.9 (2.1)% among the males and 67.4 (1.7)% among the females. Severe 25(OH)D deficiencies (<10 ng/mL) were found in 5.7 (0.8)% of the males and 11.1 (1.0)% of the females. These peaked in spring and winter. Only 12.2 (1.1)% of the males and 6.4 (0.6)% of the females exhibited 25(OH)D sufficiency (>=30 ng/mL). The correlates with higher 25(OH)D concentration for both genders included summer, fall (vs spring), the 60s age group (vs 20s), rural residence (vs urban), moderate and vigorous physical activity (vs sedentary), alcohol consumption, and multivitamin supplementation. Higher education and unmarried status were inversely associated with 25(OH)D concentration for both genders. The strongest predictors of 25(OH)D concentration were season and residential area. CONCLUSIONS:25(OH)D deficiency is a prevalent condition in Korea. Understanding the determinants of 25(OH)D can facilitate identification of persons at risk of 25(OH)D deficiency.

译文

目的:维生素D缺乏症是一种全球性的健康问题,与重大疾病的风险增加有关。这项研究调查了韩国成年人中25-羟基维生素D [25(OH)D]的状况及其人口统计学和生活方式决定因素。
方法:本研究共纳入了5847名参加了2008年韩国国家健康与营养检查调查(KNHANES)的成年人。进行逐步线性回归分析以确定25(OH)D浓度的人口统计学和生活方式决定因素。
结果:25(OH)D缺乏症(<20 ng / mL)的加权患病率(标准误)在男性中为49.9(2.1)%,在女性中为67.4(1.7)%。在男性的5.7(0.8)%和女性的11.1(1.0)%中发现了严重的25(OH)D缺陷(<10 ng / mL)。这些在春季和冬季达到顶峰。男性中只有12.2(1.1)%的女性和6.4(0.6)%的女性具有25(OH)D充足性(> = 30 ng / mL)。男女之间较高的25(OH)D浓度相关,包括夏季,秋季(春季),60岁年龄段(20岁),农村居民(城市居民),中等强度和剧烈运动(久坐),饮酒和多种维生素补充剂。高等教育和未婚状况与男女的25(OH)D浓度成反比。 25(OH)D浓度的最强预测因子是季节和居住面积。
结论:25(OH)D缺乏症在韩国很普遍。了解25(OH)D的决定因素可以帮助识别处于25(OH)D缺乏风险的人。

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