BACKGROUND:Epidemiological studies have shown significant ethnic differences in coronary heart disease death rates with South Asians showing significantly greater coronary heart disease mortality than other groups. PURPOSE:This research examined ethnic differences in cardiovascular reactivity (CVR) among Chinese, Malays and Indians in Singapore as well as a sample of Indians living in India. METHODS:Experiment 1 examined differences across 303 Chinese, Malay and Indian undergraduates in Singapore, while Experiment 2 looked at differences in CVR between Indian participants from Singapore, and 145 Indians living in India. Systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), cardiac index (CI) and total peripheral resistance index (TPRI) were measured during baselines and five laboratory tasks. RESULTS:Ethnicity main effects for SBP and CI reactivity were obtained in Experiment 1, with Indians showing significantly lower BP and CI reactivity than the Chinese and Malays. Significant main effects for sex were found with females showing lower reactivity than males for TPRI, and greater reactivity than males for HR and CI. Experiment 2 found that participants from India showed higher reactivity for SBP, HR and CI, while Indian participants from Singapore showed higher TPRI reactivity. These differences, however, often varied by task. CONCLUSIONS:These results point to differences in CVR among ethnic groups in Singapore as well as between Indians living in India and those living in Singapore. These differences may reflect cultural differences and need to be explored further with respect to their relationship to different rates of coronary heart disease among these groups.

译文

背景:流行病学研究表明,冠心病死亡率的种族差异显着,南亚人显示冠心病死亡率明显高于其他人群。
目的:本研究调查了新加坡华人,马来人和印第安人以及居住在印度的印第安人样本中心血管反应性(CVR)的种族差异。
方法:实验1考察了新加坡303名华裔,马来裔和印度裔本科生之间的差异,而实验2则考察了来自新加坡的印度裔参与者和居住在印度的145名印度裔之间的CVR差异。在基线和五个实验室任务期间测量了收缩压和舒张压(SBP,DBP),心率(HR),心脏指数(CI)和总外周阻力指数(TPRI)。
结果:种族对SBP和CI反应性的主要影响是在实验1中获得的,印度人的BP和CI反应性明显低于华人和马来人。发现性别具有重大的主要影响,女性对TPRI的反应性低于男性,而对HR和CI的反应性则高于男性。实验2发现印度参与者对SBP,HR和CI的反应性更高,而新加坡印度参与者对TPRI的反应性更高。但是,这些差异通常因任务而异。
结论:这些结果表明,新加坡各族裔之间以及居住在印度的印度人与居住在新加坡的印度人之间的CVR差异。这些差异可能反映了文化差异,因此需要进一步探讨这些差异与这些人群中冠心病发病率的关系。

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