PURPOSE OF REVIEW:The purpose of this review is to provide an update on osteoporosis epidemiology. The focus is on fractures because fractures are the most important clinical consequence of osteoporosis. Studies published over the past 18 months are identified and reviewed. Finally, the clinical impact of these new findings is discussed. RECENT FINDINGS:Important research in 2015-2016 include analyses of screening and rescreening in younger women and older men, risk factors for hip fractures in older men, obesity and weight loss/gain, and risk of fracture. Several dietary factors, including adherence to a Mediterranean diet and a diet rich in protein, fruits, and vegetables and maintenance of physical function with increasing age represent modifiable nonpharmacologic risk factors that improve bone health. Sarcopenia may have a more important role in fracture in men than women. Important biomarkers for fracture include low 25-hydroxyvitamin D and hemoglobin A1c. SUMMARY:Updated literature on fracture epidemiology have identified important risk factors for fracture.

译文

审查的目的:这次审查的目的是提供有关骨质疏松症流行病学的最新信息。重点是骨折,因为骨折是骨质疏松症最重要的临床后果。确定并审查过去18个月内发表的研究。最后,讨论了这些新发现的临床影响。
最新发现:2015-2016年的重要研究包括对年轻女性和老年男性进行筛查和再筛查,老年男性髋部骨折的危险因素,肥胖和体重减轻/增重以及骨折的风险的分析。几种饮食因素,包括坚持地中海饮食以及富含蛋白质,水果和蔬菜的饮食,以及随着年龄的增长而保持身体机能,这些都是改善骨骼健康的可改变的非药理危险因素。肌肉减少症在男性骨折中可能比女性更重要。骨折的重要生物标志物包括低25-羟基维生素D和血红蛋白A1c。
摘要:关于骨折流行病学的最新文献已经确定了骨折的重要危险因素。

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