OBJECTIVE:To discover potential differences in known prognostic factors of renal adenocarcinoma in patients under 40 years of age. PATIENTS AND METHODS:A series of 246 patients with renal adenocarcinoma included 17 patients 40 years. Both groups were analyzed for sex, tumour size, histological characteristics and stage, examining the relative proportions within each group and looking for an association between those sets of data and age. RESULTS:No statistically significant associations were found, although it should be noted that in some cases data is incomplete. A larger proportion of low stages at least locally and a greater proportion of granule cell tumours was found in patients 40 years-old compared to those over 40. CONCLUSIONS:Existence of differences in the biological and histological characteristics of renal adenocarcinomas that develop at a younger age is not unlikely. The analysis of each factor and the survival rates in larger series should elucidate these questions, which will also be of interest to improve our understanding of the histogenesis of this type of tumours.

译文

目的:探讨40岁以下患者肾腺癌的预后因素之间的潜在差异。
患者与方法:246例肾腺癌患者中包括17例40岁的患者。分析两组的性别,肿瘤大小,组织学特征和分期,检查每组内的相对比例,并寻找这些数据与年龄之间的关联。
结果:尽管在某些情况下数据不完整,但未发现统计学上显着的关联。与40岁以上的患者相比,在40岁的患者中,至少局部存在较低比例的低分期,并且颗粒细胞肿瘤的比例更高。
结论:年轻时发生的肾腺癌的生物学和组织学特征存在差异的可能性不大。在较大系列中对每个因素和存活率的分析应阐明这些问题,这对于增进我们对这种类型肿瘤的组织发生的理解也将是有益的。

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