OBJECTIVE:In healthy controls, the emotional charge of stimuli influences how well stimuli are remembered. Although patients with schizophrenia (SCZ) have deficits in memory and in emotional processing, studies on emotional memory modulation (EMM) in SCZ report contradictory results. The aim of this review was to investigate whether methodological differences could explain these contradictory results. METHOD:We reviewed the literature to investigate whether task differences could explain these differences. Due to the methodological differences, a meta-analysis was not possible. RESULTS:Fourteen studies were identified that used a total of 22 tasks to study EMM in patients with SCZ. Two-thirds of the tasks showed no differences in EMM between patients with SCZ and healthy controls. Differences in EMM were found more often when long-term compared to short-term memory was measured, when memory instructions were implicit instead of explicit and when stronger emotional stimuli were used. An overall memory deficit or the mode of retrieval was not related to EMM. CONCLUSION:Deficits in EMM in long-term compared to short-term memory point toward impaired emotional modulation of memory consolidation. Reduced EMM on implicit, but not explicit, tasks suggests a deficit in unconsciously using emotional content to modulate memory.

译文

目的:在健康的对照组中,刺激的情绪影响会影响人们对刺激的记忆程度。尽管精神分裂症(SCZ)患者的记忆力和情绪加工能力存在缺陷,但SCZ的情绪记忆调节(EMM)研究显示出矛盾的结果。这篇综述的目的是调查方法学上的差异是否可以解释这些矛盾的结果。
方法:我们回顾了文献,以调查任务差异是否可以解释这些差异。由于方法上的差异,无法进行荟萃分析。
结果:确定了十四项研究,总共使用了22个任务来研究SCZ患者的EMM。三分之二的任务显示SCZ患者和健康对照者之间的EMM无差异。当测量长期记忆与短期记忆相比,当记忆指令是隐式而非显式的,并且使用了较强的情绪刺激时,EMM的差异更常见。整体内存不足或检索模式与EMM不相关。
结论:与短期记忆相比,长期EMM缺陷表明记忆整合的情绪调节受损。隐式但非显式任务的EMM减少表明在不知不觉中使用情感内容来调节记忆的缺陷。

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