BACKGROUND:Intralesional triamcinolone is an established therapy for cysts of acne. However, intralesional antibacterials have not been used earlier. AIM:To compare the efficacy of intralesional triamcinolone with that of a combination of intralesional lincomycin and intralesional triamcinolone in nodulocystic acne. MATERIAL AND METHODS:Ten patients of nodulocystic were injected with intralesional triamcinolone acetonide (2.5 mg/ml), while nine patients were given lincomycin hydrochloride (75 mg/ml) in addition to the intralesional triamcinolone. They were followed up 48 hrs, one week and one month later. RESULTS:At one week, 7 patients (70%) treated with injection triamcinolone showed 66% improvement, whereas all 9 (100%) patients treated with lincomycin and triamcinolone showed 100% improvement which was stable at one month. CONCLUSION:A combination of intralesional triamcinolone and lincomycin is superior to intralesional triamcinolone alone in the treatment of nodulocystic lesions of acne.

译文

背景:曲安奈德是一种治疗痤疮囊肿的既定疗法。但是,病灶内的抗菌剂尚未被较早使用。
目的:比较病灶内曲安奈德与病灶内林可霉素和病灶内曲安奈德联合治疗结节性囊性痤疮的疗效。
材料与方法:十例结节性囊肿患者均注射了病灶内曲安奈德(2.5 mg / ml),而9名患者除病灶内曲安奈德外还注射了盐酸林可霉素(75 mg / ml)。一星期零一个月后,他们接受了48小时的随访。
结果:在一周内,注射曲安奈德治疗的7例患者(70%)表现出66%的改善,而用林可霉素和曲安奈德治疗的9例患者(100%)表现出100%的改善,在一个月内稳定。
结论:病灶内曲安奈德和林可霉素联合治疗在痤疮结节性囊性病变中优于单独病灶内曲安奈德。

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