BACKGROUND:Successful thromboendarterectomy for chronic thromboembolic pulmonary hypertension promptly improves right ventricular (RV) function by decreasing RV volume and increasing ejection fraction (EF). Single photon emission computed tomography (SPECT) equilibrium radionuclide angiocardiography (ERNA) has been validated as a measure of RV and left ventricular (LV) volume and EF.
METHODS AND RESULTS:Nine patients with chronic thromboembolic pulmonary hypertension underwent electron beam computed tomography (EBCT) and SPECT ERNA cardiac studies before and after thromboendarterectomy. EBCT and SPECT ERNA measures of RV and LV volume and EF were compared. Before thromboendarterectomy, EBCT and SPECT ERNA RV and LV volumes and RV EF were similar. LV EF was within the normal range with both methods but was slightly greater (P = .004) when measured by EBCT (mean +/- SD, 0.61 +/- 0.08) compared with SPECT ERNA (0.54 +/- 0.10). Thromboendarterectomy measured by EBCT and SPECT ERNA produced marked similar and significant decreases in RV end-systolic (-72 +/- 59 mL vs -58 +/- 25 mL) and end-diastolic (-75 +/- 85 mL vs -76 +/- 32 mL) volumes and similar slight increases in RV EF (0.12 +/- 0.07 vs 0.05 +/- 0.06). Slight decreases in mean LV end-systolic (-19 +/- 23 mL vs -5 +/- 13 mL, P = .05) and end-diastolic (-32 +/- 53 mL vs -9 +/- 31 mL, P = .21) volumes occurred, with little change in mean LV EF (0.05 +/- 0.07 vs 0.00 +/- 0.10).
CONCLUSIONS:SPECT ERNA is an accurate method for measuring RV and LV volume and EF before and after thromboendarterectomy.
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【Assessment of pulmonary thromboendarterectomy by tomographic electrocardiogram-gated equilibrium radionuclide angiocardiography compared with electron beam computed tomography.].
【与电子束计算机断层扫描相比，通过断层扫描心电图门控平衡放射性核素血管造影术评估肺血栓内膜切除术。】
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DOI：10.1016/j.nuclcard.2006.09.009文章类型：杂志文章
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背景：成功的用于慢性血栓栓塞性肺动脉高压的血栓内膜切除术可通过减少RV体积和增加射血分数（EF）迅速改善右心室（RV）功能。单光子发射计算机断层扫描（SPECT）平衡放射性核素血管造影（ERNA）已被验证为RV和左心室（LV）体积和EF的量度。
方法和结果：9例慢性血栓栓塞性肺动脉高压患者在血栓内膜切除术前后均接受了电子束计算机断层扫描（EBCT）和SPECT ERNA心脏检查。比较了RVCT和LV体积以及EF的EBCT和SPECT ERNA测量值。血栓内膜切除术之前，EBCT和SPECT ERNA的RV和LV体积以及RV EF相似。两种方法的LV EF均在正常范围内，但与SPECT ERNA（0.54 /-0.10）相比，通过EBCT测量时，LV EF略高（P = .004）（平均值/-SD，0.61 /-0.08）。通过EBCT和SPECT ERNA测量的血栓内膜切除术在RV收缩末期（-72 /-59 mL对-58 /-25 mL）和舒张末期（-75 /-85 mL对-76 /-32）产生了相似且显着的降低毫升）体积和RV EF的类似轻微增加（0.12 / 0.07比0.05 / 0.06）。平均LV收缩末期（-19 /-23 mL vs --5 /-13 mL，P = .05）和舒张末期（-32 /-53 mL vs -9 /-31 mL，P =。 21）出现体积，平均LV EF几乎没有变化（0.05 /-0.07对0.00 /-0.10）。
结论：SPECT ERNA是在血栓内膜切除术前后测量RV，LV体积和EF的准确方法。
方法和结果：9例慢性血栓栓塞性肺动脉高压患者在血栓内膜切除术前后均接受了电子束计算机断层扫描（EBCT）和SPECT ERNA心脏检查。比较了RVCT和LV体积以及EF的EBCT和SPECT ERNA测量值。血栓内膜切除术之前，EBCT和SPECT ERNA的RV和LV体积以及RV EF相似。两种方法的LV EF均在正常范围内，但与SPECT ERNA（0.54 /-0.10）相比，通过EBCT测量时，LV EF略高（P = .004）（平均值/-SD，0.61 /-0.08）。通过EBCT和SPECT ERNA测量的血栓内膜切除术在RV收缩末期（-72 /-59 mL对-58 /-25 mL）和舒张末期（-75 /-85 mL对-76 /-32）产生了相似且显着的降低毫升）体积和RV EF的类似轻微增加（0.12 / 0.07比0.05 / 0.06）。平均LV收缩末期（-19 /-23 mL vs --5 /-13 mL，P = .05）和舒张末期（-32 /-53 mL vs -9 /-31 mL，P =。 21）出现体积，平均LV EF几乎没有变化（0.05 /-0.07对0.00 /-0.10）。
结论：SPECT ERNA是在血栓内膜切除术前后测量RV，LV体积和EF的准确方法。
