PURPOSE:To investigate the effect of warmup by application of the thermal agent Deep Heat (DH) on muscle mechanical properties using magnetic resonance elastography (MRE) at 3T before and after exercise-induced muscle damage (EIMD). MATERIALS AND METHODS:Twenty male participants performed an individualized protocol designed to induce EIMD in the quadriceps. DH was applied to the thigh in 50% of the participants before exercise. MRE, T2 -weighted MRI, maximal voluntary contraction (MVC), creatine kinase (CK) concentration, and muscle soreness were measured before and after the protocol to assess EIMD effects. Five participants were excluded: four having not experienced EIMD and one due to incidental findings. RESULTS:Total workload performed during the EIMD protocol was greater in the DH group than the control group (P < 0.03), despite no significant differences in baseline MVC (P = 0.23). Shear stiffness |G*| increased in the rectus femoris (RF) muscle in both groups (P < 0.03); however, DH was not a significant between-group factor (P =  0.15). MVC values returned to baseline faster in the DH group (5 days) than the control group (7 days). Participants who displayed hyperintensity on T2 -weighted images had a greater stiffness increase following damage than those without: RF; 0.61 kPa vs. 0.15 kPa, P < 0.006, vastus intermedius; 0.34 kPa vs. 0.03 kPa, P = 0.06. CONCLUSION:EIMD produces increased muscle stiffness as measured by MRE, with the change in |G*| significantly increased when T2 hyperintensity was present. DH did not affect CK concentration or soreness; however, DH participants produced greater workload during the EIMD protocol and exhibited accelerated MVC recovery. LEVEL OF EVIDENCE:1 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2017;46:1115-1127.

译文

目的:研究在运动诱发的肌肉损伤(EIMD)前后,在3T时使用磁共振弹性成像(MRE)来施加热剂深热(DH)对肌肉力学性能的热身作用。
材料与方法:二十名男性受试者进行了个性化设计,旨在诱发股四头肌EIMD。在运动前,将DH应用于50%的参与者的大腿上。在评估EIMD效果之前和之后,测量了MRE,T2加权MRI,最大自愿收缩(MVC),肌酸激酶(CK)浓度和肌肉酸痛。五名参与者被排除在外:四名未经历过EIMD,一名因偶然发现。
结果:尽管基线MVC无显着差异(P = 0.23),但DH组在EIMD方案期间执行的总工作量大于对照组(P <0.03)。剪切刚度| G * |两组的股直肌(RF)肌肉均增加(P <0.03);然而,DH不是一个显着的组间因素(P = 0.15)。在DH组(5天)中,MVC值返回基线的速度比对照组(7天)更快。与没有以下情况的参与者相比,在T2加权图像上表现出高强度的参与者在受到损伤后的刚度增加更大。 0.61 kPa和0.15 kPa,P <0.006,中间臀大肌; 0.34 kPa对0.03 kPa,P = 0.06。
结论:通过| MRE测量,EIMD产生增加的肌肉僵硬度,| G * |的变化。存在T2高强度时,血红蛋白显着增加。 DH不影响CK浓度或酸痛;但是,DH参与者在EIMD协议期间产生了更大的工作量,并表现出加速的MVC恢复。
证据级别:1技术效力:第2阶段。雷森成像2017; 46:1115-1127。

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