OBJECTIVE:Our aim was to investigate how dyslipidemia was diagnosed and treated in patients with peripheral artery disease (PAD) in a university vascular clinic. DESIGN:Our analysis included all 1 843 PAD patients (median age 71 years, interquartile range 63-79, M/W 975/868) who attended the clinic in 2002-2003 either for diagnostic angiography or for revascularization. The charts of patients tested for dyslipidemia were reviewed closer. RESULTS:Serum lipids were measured in only 214 PAD patients (11.6%). Of them 37.9% smoked, 59.8% had antihypertensive medication, 35.0% diabetes, and 30.8% a history of coronary heart disease. Mean serum cholesterol concentration was 4.5 mmol/l (SD 1.3), LDL-cholesterol 2.54 (0.48), HDL-cholesterol 1.25 (0.48), and triglycerides 1.62 (0.84). Only 40 patients (19.7%) were using statins, this was increased to 72 (33.6%) after clinic visit. Consequently, 50.0% and 53.2% met the current total cholesterol (<4.5 mmol/l) and LDL-cholesterol (<2.5 mmol/l) goals, respectively. CONCLUSIONS:Dyslipidemia was highly under-diagnosed among PAD patients. Serum lipids were measured only in a minority and among them serum lipid values and the use of hypolipidemic drugs were not optimal according to guidelines.

译文

目的:我们的目的是研究在大学血管诊所对患有外周动脉疾病(PAD)的患者进行血脂异常的诊断和治疗的方法。
设计:我们的分析包括2002年至2003年就诊于诊断性血管造影或血管重建术的所有1843名PAD患者(中位年龄71岁,四分位间距63-79,M / W 975/868)。血脂异常检查患者的病历表进行了仔细回顾。
结果:仅214名PAD患者中测量了血清脂质(11.6%)。其中37.9%的吸烟者,59.8%的患者服用降压药,35.0%的糖尿病患者和30.8%的冠心病史。平均血清胆固醇浓度为4.5 mmol / l(SD 1.3),LDL-胆固醇2.54(0.48),HDL-胆固醇1.25(0.48)和甘油三酸酯1.62(0.84)。只有40例患者(19.7%)使用他汀类药物,到诊所就诊后增加到72例(33.6%)。因此,分别达到当前总胆固醇(<4.5 mmol / l)和LDL-胆固醇(<2.5 mmol / l)的目标的分别为50.0%和53.2%。
结论:PAD患者的血脂异常被高度诊断不足。仅在少数人群中测量了血脂,其中血脂值和降血脂药物的使用不是根据指南的最佳方法。

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