The present investigation describes the effect on the isolated rat ileum of methanolic extracts derived from Conyza filaginoides (D. C.) Hieron (Asteraceae), Croton fragilis HBK. (Euphorbiaceae), Dodonaea viscosa Jacq. (Sapindaceae), Gymnosperma glutinosum (Spreng) Less. (Asteraceae), Parthenium tomentosum DC. var. stramonium (Greene) Rollins (Asteraceae), Potentilla thurberi A. Gray (Rosaceae), Pterogonum atrorubens (Englem.) H. Gross (Polygonaceae), Zornia venosa Mohlenbr. (Fabaceae) and Datura lanosa Barclay ex Bye (Solanaceae). In all the cases the extracts inhibited, in a concentration-dependent manner, the spontaneous contraction of the intestinal smooth muscle. The most active extract was that of D. viscosa. These findings tend to support the ethnomedical use of the selected species as spasmolytic agents in Mexican traditional medicine. Additionally, the potential antimicrobial activity of the extracts against pathogenic enterobacteria was investigated. Seven of the nine plants evaluated displayed antibacterial effects.
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【Spasmolytic potential of some plants used in Mexican traditional medicine for the treatment of gastrointestinal disorders.].
【墨西哥传统医学中用于治疗胃肠道疾病的某些植物的痉挛潜力。】
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DOI：10.1016/S0944-7113(11)80049-8文章类型：杂志文章
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：本研究描述了从Conyza filaginoides（D. C.）Hieron（Asteraceae），脆弱的巴豆HBK提取的甲醇提取物对离体大鼠回肠的作用。 （大戟科），Dodonaea viscosa Jacq。 （无患子科），裸子植物（Gymnosperma glutinosum）（Spreng）少。 （菊科），Parthenium tomentosum DC。变种amo（Greene）罗林斯（菊科），委陵菜A. Gray（蔷薇科），翼龙（Pterogonum atrorubens）（英）H. Gross（Po科），百日草（Zornia venosa Mohlenbr）。 （Fabaceae）和Datura lanosa Barclay ex Bye（Solanaceae）。在所有情况下，提取物均以浓度依赖性方式抑制肠平滑肌的自发收缩。活性最高的提取物是粘枝梭状芽胞杆菌。这些发现倾向于支持在种族学上将所选物种用作墨西哥传统医学中的解痉剂。此外，还研究了提取物对病原性肠杆菌的潜在抗菌活性。评估的9株植物中有7株显示出抗菌作用。
