A 34-year-old woman developed nephrotic syndrome after using a skin lightening cream that contained an extremely high level of mercury. Blood and urine mercury levels were elevated and a renal biopsy revealed minimal change disease. Membranous nephropathy was excluded using immunofluorescence and electron microscopy. Her proteinuria remitted 9 months after she stopped using the cosmetic cream. This is the first reported case in the English literature of proven minimal change disease secondary to mercury exposure. It is important that mercury poisoning due to cosmetic cream is considered in the differential diagnoses for any woman who presents with nephrotic syndrome.

译文

:一名34岁的女性在使用含有极高汞含量的亮肤霜后患上了肾病综合症。血液和尿液中的汞含量升高,肾脏活检显示病变最小。使用免疫荧光和电子显微镜排除了膜性肾病。停止使用美容霜后9个月,她的蛋白尿症状得到缓解。这是英国文献中首次报道的继汞暴露后引起的最小变化疾病的病例。对于所有患有肾病综合征的女性,在鉴别诊断中都应考虑到由于美容霜引起的汞中毒。

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