PURPOSE:The distribution, content, timeliness, use, and influence of pharmacoeconomic assessments (PEAs) of drugs in New Zealand public hospitals were examined. METHODS:In April 2005, a questionnaire-based, cross-sectional survey was sent to chief pharmacists at all 29 New Zealand hospitals employing a pharmacist. The questionnaire asked pharmacists about the use and influence of PEAs in their hospitals' formulary decision-making process. Answers were given using a scale of 1 to 6, with 1 being the most positive response. RESULTS:Of the 29 surveys mailed, 24 (83%) were completed. Data on 12 PEAs were analyzed. Assessments were seen and summaries read in most hospitals (median, 77% and 65%, respectively). Full documents were read in fewer hospitals (35%). In general, the PEAs were considered moderately easy to understand, provided a concise summary, and contained adequate detail of the methodology. Of the 24 respondent hospitals, 21 had assessment processes for new medicines; hence, a total of 252 hospital evaluations of Pharmaceutical Management Agency (PHARMAC)-assessed drugs were possible. A total of 132 possible evaluations (52%) were undertaken. More evaluations (106 [42%]) took place before PHARMAC's PEAs were distributed and fewer (26 [10%]) after distribution. Where used, the PEAs appeared to have a modest effect on hospital decisions. CONCLUSION:The provision of 12 PEAS by PHARMAC to hospitals in New Zealand had only a modest influence on their formulary decision-making process, mostly due to the lack of timeliness of the PEAs. The timely delivery of centrally developed PEAs may be essential to generating a greater effect on the formulary decisions at a wider level.

译文

目的:检查了新西兰公立医院药物的药物经济评估(PEA)的分布,内容,及时性,使用和影响。
方法:2005年4月,基于问卷调查的横断面调查被发送给新西兰所有29家雇用药剂师的医院的首席药剂师。该问卷向药剂师询问了PEA在其医院处方制定决策过程中的使用和影响。答案以1到6的等级给出,其中1是最积极的回答。
结果:在邮寄的29份调查中,有24份(83%)已完成。分析了12个PEA的数据。大多数医院都进行了评估并阅读了摘要(中位数分别为77%和65%)。较少的医院(35%)读取了完整的文档。一般而言,PEA被认为具有中等程度的易懂性,提供了简洁的摘要,并包含了该方法的足够详细信息。在24家受访医院中,有21家拥有新药评估程序;因此,总共可以对252个由美国药物管理局(PHARMAC)评估的药物进行医院评估。总共进行了132次可能的评估(52%)。在分发PHARMAC的PEA之前进行了更多的评估(106 [42%]),而在分发之后进行的评估较少(26 [10%])。在使用PEA的情况下,似乎对医院的决策影响不大。
结论:PHARMAC向新西兰的医院提供了12个PEAS,对他们的处方制定决策过程影响不大,这主要是由于PEAs缺乏及时性。及时提供集中开发的PEA对于在更大范围内对配方决策产生更大影响可能是必不可少的。

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