Percutaneous transluminal coronary angioplasty (PTCA) with stent implantation is widely used for the treatment of coronary stenosis. However, restenosis after stent implantation frequently reported by intravascular ultrasound evaluation. This may occur because of the reduced luminal area after implantation, insufficient stent expansion, or by the elastic recoil of the stent (ERS). Quantitative evaluation of stent expanding should provide further information on how to decrease the incidence of re-stenosis. Many previous studies have observed stent properties in 2D. However, the stent geometry is changed in 3D space, and 3D measurements will provide further information on factors such as the risk for asymmetric ERS. We performed 3D reconstruction using high spatial resolution images obtained with a Micro-CT system to observe the 3D expansion behavior of a test stent and quantitatively evaluate ERS. The expansion behavior of each structural component of the stent varied, as did the ERS and eccentricity. ERS ranged from 2.4% to 9.2% during observation form proximal and distal positions in each component. The greatest difference in ERS between 2D and 3D measurements was 5.2%. 3D measurements provide more information on ERS than 2D measurements. Our result shows the importance of the observation, and the evaluation by three dimensions.

译文

经皮冠状动脉腔内成形术 (PTCA) 与支架植入术广泛用于治疗冠状动脉狭窄。然而,血管内超声评估经常报告支架植入后的再狭窄。这可能是由于植入后管腔面积减小,支架扩张不足或支架的弹性反冲 (ERS) 引起的。支架扩张的定量评估应提供有关如何减少再狭窄发生率的进一步信息。以前的许多研究都在2D中观察到了支架的特性。但是,支架的几何形状在3D空间中会发生变化,并且3D测量将提供有关诸如不对称ERS风险等因素的进一步信息。我们使用Micro-CT系统获得的高空间分辨率图像进行了3D重建,以观察测试支架的3D扩展行为并定量评估ERS。支架的每个结构组件的膨胀行为以及ERS和偏心率都有所不同。在观察期间,每个组件的近端和远端位置的ERS范围从2.4% 到9.2%。2D和3D测量之间的ERS的最大差异是5.2%。3D测量比2D测量提供更多关于ERS的信息。我们的结果显示了观察的重要性,并通过三个维度进行了评估。

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