This study describes 5 infants who were diagnosed with auditory neuropathy (AN) associated with severe to profound neural hearing loss shortly after birth. However, on repetition of the tests 7-12 months later, all infants showed full or partial recovery. The follow-up electrophysiological patterns were characterized by the appearance of wave I, followed by wave III and V, reflecting synchronization of auditory pathways and improvement in auditory nerve function. Suspected causative or contributory factors were neonatal hyperbilirubinemia, hypoxia, ischemia, and central nervous system immaturity, alone or in combination. These findings indicate that lack of an auditory brain stem response does not necessarily mean no hearing and that the situation where AN exists can improve. Thus, clinicians should be made aware that although cochlear implants may yield better auditory performance when applied early, they should be considered a therapeutic option only after repeated measures have proved persistent AN, and no child should be considered for an implant until a behavioral measure of hearing has been obtained.

译文

这项研究描述了5名婴儿,他们在出生后不久被诊断出患有听觉神经病 (AN),并伴有严重至严重的神经听力损失。然而,在7-12个月后重复测试时,所有婴儿均显示完全或部分康复。随访电生理模式的特征是出现I波,其次是III波和V波,反映了听觉通路的同步和听觉神经功能的改善。可疑的病因或促成因素是新生儿高胆红素血症,缺氧,缺血和中枢神经系统不成熟,单独或联合使用。这些发现表明,缺乏听觉脑干反应并不一定意味着没有听力,并且存在的情况可以改善。因此,临床医生应该意识到,尽管人工耳蜗植入在早期应用时可能会产生更好的听觉性能,但只有在重复测量证明持续存在后,才应将其视为治疗选择,并且在行为测量之前,不应考虑将儿童植入植入物。已获得听力。

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