This retrospective study is armed to indicate the descriptive and pathological aspects of children Burkitt lymphoma in Cameroon. It was performed on a 4 year period between July 1988 and July 1992. Children from 0 to 15-year-old who were hospitalized and who had histologically provern Burkitt lymphoma were included. There were 39 patients, that is 27% of all malignant tumors in children during this period. Twenty-four were boys and 15 were girls; the median age was 90 months (+/-46) (range from 3 to 180 months). All children had Plasmodium falciparum infection. EBV serology was positive in 18 patients out of 25 (72%), 14 (36%) had a good nutritional status, the 25 other patients suffered malnutrition. Tumor localizations weremaxillary in 29 (74%) patients, abdominal in 7 (18%), other in 3 patients.

Clinical stages according to Murphy classification werestage I in 6 (15%) patients, II in 3 (8%), III in 20 (51%) and IV in 10 (26%). It is concluded from this series that clinical aspects and histological pattern in children Burkitt lymphoma in Cameroon are not different from what is observed in other endemic areas.

译文

这项回顾性研究旨在表明喀麦隆儿童伯基特淋巴瘤的描述性和病理性。该研究在1988年7月至1992年7月的4年时间内进行。其中包括0至15岁住院且经组织学证实为Burkitt淋巴瘤的儿童。有39例患者,占此期间儿童所有恶性肿瘤的27%。二十四岁是男孩,十五岁是女孩;中位年龄为90个月(/ -46)(从3到180个月不等)。所有儿童均患有恶性疟原虫感染。 EBV血清学阳性的25例患者中有18例(72%),营养状况良好的14例(36%),其他25例营养不良。肿瘤定位在29例(74%)为上颌骨,腹部在7例(18%)中,其他在3例中。根据墨菲分类的临床分期为I期的6例(15%),II期的3例( 8%),三分之二(51%)和四分之十(26%)。从该系列中得出的结论是,喀麦隆儿童Burkitt淋巴瘤的临床表现和组织学模式与在其他流行地区所观察到的没有什么不同。

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