• 【简要交流: 退休期间医生对志愿服务的兴趣。】 复制标题 收藏 收藏
    DOI:10.7326/0003-4819-149-5-200809020-00006 复制DOI
    作者列表:Sloane PD,Cohen LW,Konrad TR,Williams CS,Schumacher JG,Zimmerman S
    BACKGROUND & AIMS: BACKGROUND:Baby boomers approaching retirement will include unprecedented numbers of physicians, many of whom want to remain productive. OBJECTIVE:To determine interest in health care-related volunteering during retirement among physicians trained to provide general medical care to adults. DESIGN:Cross-sectional mailed survey conducted May through July 2006. SETTING:North Carolina. PARTICIPANTS:910 physicians, 55 years of age or older, whose primary specialty involved direct, nonsurgical care of adults. MEASUREMENTS:Current volunteerism and future interest in selected activities. RESULTS:Of the respondents, 89.8% were male and 87.4% were white; 57.4% worked full-time, 21.7% worked part-time, and 21.0% were retired. Of current retirees, 37.1% expressed interest in volunteering. Areas of greatest interest were medical teaching, working in free medical clinics, and international care. Strong incentives included staying mentally active (67.3%) or involved in medicine (61.2%) and contributing to society (60.5%). Substantial barriers included concerns about malpractice (61.5%) and paperwork or bureaucracy (46.0%). The majority of respondents (66.7%) felt that lack of payment would not influence volunteering. LIMITATIONS:The 59% overall response rate and exclusion of unlicensed retired physicians limit study generalizability. The data were provided by self-response and could not be independently validated. CONCLUSION:Retired physicians are a potential source of manpower that could contribute to provision of health care, particularly in medical teaching and clinical care of underserved persons.
    背景与目标:
  • 【关于生命即将结束的癌症的交流。】 复制标题 收藏 收藏
    DOI:10.1002/cncr.23653 复制DOI
    作者列表:Back AL,Anderson WG,Bunch L,Marr LA,Wallace JA,Yang HB,Arnold RM
    BACKGROUND & AIMS: :Cancer communication near the end of life has a growing evidence base, and requires clinicians to draw on a distinct set of communication skills. Patients with advanced and incurable cancers are dealing with the emotional impact of a life-limiting illness, treatment decisions that are complex and frequently involve consideration of clinical trials, and the challenges of sustaining hope while also having realistic goals. In this review, the authors sought to provide a guide to important evidence about communication for patients with advanced cancer regarding communication at diagnosis, discussing prognosis, decision making about palliative anticancer therapy and phase 1 trials, advance care planning, transitions in focus from anticancer to palliative care, and preparing patients and families for dying and death.
    背景与目标: : 生命即将结束的癌症交流具有越来越多的证据基础,并且要求临床医生利用一套独特的交流技巧。患有晚期和无法治愈的癌症的患者正在处理限制生命的疾病的情感影响,复杂且经常涉及临床试验的治疗决策,以及在维持希望的同时也具有现实目标的挑战。在这篇综述中,作者试图为晚期癌症患者的沟通提供重要证据指南,包括诊断时的沟通,讨论预后,姑息抗癌治疗的决策和1期试验,预先护理计划,从抗癌到姑息治疗的重点过渡,让病人和家人为死亡做好准备。
  • 【患者接受癌症诊断的沟通偏好: 取决于癌症分期的差异。】 复制标题 收藏 收藏
    DOI:10.1002/pon.5447 复制DOI
    作者列表:Kim SH,Kim JH,Shim EJ,Hahm BJ,Yu ES
    BACKGROUND & AIMS: OBJECTIVE:This study aimed to identify communication preferences for receiving a cancer diagnosis in South Korean patients and explore differences depending on cancer stage-with or without recurrence/metastasis. METHODS:A total of 312 patients from five cancer centers in South Korea completed the Korean version of the Measure of Patients' Preferences questionnaire, Mini-Mental Adjustment to Cancer scale, Insomnia Severity Index, and Hospital Anxiety and Depression Scale. RESULTS:Among patients without recurrence/metastasis, four factors were indicated: "additional information," "medical information," "emotional support," and "supportive environment." Among patients with recurrence/metastasis, five factors were indicated: "medical information and explanation," "emotional support," "supportive environment," "additional information," and "informing family." In the group without recurrence/metastasis, a positive attitude was a significant predictor of the preference for all four factors and a lower anxiety level was a predictor of the preference for additional information. Patients who reported a high level of anxious preoccupation preferred supportive environments. In the group with recurrence/metastasis, patients who showed a high level of cognitive avoidance preferred to receive medical and additional information and emotional support. CONCLUSIONS:Cancer patients' preferences for communication when receiving bad news differ whether recurrence/metastasis or not in South Korea. Especially, patients with recurrence/metastasis preferred a clear explanation of medical information, and physicians informing patients' families about their diagnosis and prognosis. Thus, physicians should take patients' medical and psychological characteristics into consideration when delivering the news regarding their condition.
    背景与目标:
  • 【妇科癌症中PI3K/AKT/mTOR通路与Y-box结合蛋白-1的通讯。】 复制标题 收藏 收藏
    DOI:10.3390/cancers12010205 复制DOI
    作者列表:Sobočan M,Bračič S,Knez J,Takač I,Haybaeck J
    BACKGROUND & AIMS: :Studies of the mechanistic (mammalian) target of rapamycin inhibitors (mTOR) represent a step towards the targeted treatment of gynecological cancers. It has been shown that women with increased levels of mTOR signaling pathway targets have worse prognosis compared to women with normal mTOR levels. Yet, targeting mTOR alone has led to unsatisfactory outcomes in gynecological cancer. The aim of our review was therefore to provide an overview of the most recent clinical results and basic findings on the interplay of mTOR signaling and cold shock proteins in gynecological malignancies. Due to their oncogenic activity, there are promising data showing that mTOR and Y-box-protein 1 (YB-1) dual targeting improves the inhibition of carcinogenic activity. Although several components differentially expressed in patients with ovarian, endometrial, and cervical cancer of the mTOR were identified, there are only a few investigated downstream actors in gynecological cancer connecting them with YB-1. Our analysis shows that YB-1 is an important player impacting AKT as well as the downstream actors interacting with mTOR such as epidermal growth factor receptor (EGFR), Snail or E-cadherin.
    背景与目标: : 雷帕霉素抑制剂 (mTOR) 的机制 (哺乳动物) 靶标的研究代表了妇科癌症靶向治疗的一步。研究表明,与mTOR水平正常的女性相比,mTOR信号通路靶标水平升高的女性预后较差。然而,单独靶向mTOR导致妇科癌症的结果不令人满意。因此,我们审查的目的是概述妇科恶性肿瘤中mTOR信号传导和冷休克蛋白相互作用的最新临床结果和基本发现。由于其致癌活性,有前景的数据表明mTOR和Y-box蛋白1 (YB-1) 双重靶向改善了对致癌活性的抑制。尽管在mTOR的卵巢癌,子宫内膜和宫颈癌患者中发现了几种差异表达的成分,但在妇科癌症中只有少数研究的下游参与者将其与YB-1联系起来。我们的分析表明,YB-1是影响AKT以及与mTOR相互作用的下游参与者的重要参与者,例如表皮生长因子受体 (EGFR),蜗牛或E-cadherin。
  • 【FGF和细胞外信号调节激酶在晶状体间隙连接介导的细胞间通讯中的新作用。】 复制标题 收藏 收藏
    DOI:10.1083/jcb.200101057 复制DOI
    作者列表:Le AC,Musil LS
    BACKGROUND & AIMS: :Gap junction-mediated intercellular coupling is higher in the equatorial region of the lens than at either pole, a property believed to be essential for lens transparency. We show that fibroblast growth factor (FGF) upregulates gap junctional intercellular dye transfer in primary cultures of embryonic chick lens cells without detectably increasing either gap junction protein (connexin) synthesis or assembly. Insulin and insulin-like growth factor 1, as potent as FGF in inducing lens cell differentiation, had no effect on gap junctions. FGF induced sustained activation of extracellular signal-regulated kinase (ERK) in lens cells, an event necessary and sufficient to increase gap junctional coupling. We also identify vitreous humor as an in vivo source of an FGF-like intercellular communication-promoting activity and show that FGF-induced ERK activation in the intact lens is higher in the equatorial region than in polar and core fibers. These findings support a model in which regional differences in FGF signaling through the ERK pathway lead to the asymmetry in gap junctional coupling required for proper lens function. Our results also identify upregulation of intercellular communication as a new function for sustained ERK activation and change the current paradigm that ERKs only negatively regulate gap junction channel activity.
    背景与目标: : 间隙连接介导的细胞间耦合在晶状体的赤道区域比在任一极处都要高,这一特性被认为对晶状体透明性至关重要。我们显示,成纤维细胞生长因子 (FGF) 在胚胎雏鸡晶状体细胞的原代培养物中上调间隙连接细胞间染料转移,而不会明显增加间隙连接蛋白 (连接蛋白) 的合成或组装。胰岛素和胰岛素样生长因子1在诱导晶状体细胞分化方面与FGF一样有效,对间隙连接没有影响。FGF诱导晶状体细胞中细胞外信号调节激酶 (ERK) 的持续激活,这是增加间隙连接偶联所必需且足以的事件。我们还将玻璃体液鉴定为FGF样细胞间通讯促进活性的体内来源,并表明完整晶状体中FGF诱导的ERK激活在赤道区域高于极性和核心纤维。这些发现支持一个模型,在该模型中,通过ERK途径的FGF信号传导的区域差异导致适当的晶状体功能所需的间隙连接耦合的不对称性。我们的结果还确定了细胞间通讯的上调是持续ERK激活的新功能,并改变了ERKs仅负调节间隙连接通道活性的当前范例。
  • 【评估创伤性脑损伤患者有偿护理人员的沟通培训。】 复制标题 收藏 收藏
    DOI:10.3109/02699052.2012.722258 复制DOI
    作者列表:Behn N,Togher L,Power E,Heard R
    BACKGROUND & AIMS: PRIMARY OBJECTIVE:To evaluate the effectiveness of a communication training programme for paid carers to improve their conversational interactions with people with TBI. RESEARCH DESIGN:Single blinded randomized controlled study. METHODS AND PROCEDURES:Ten paid carers were randomly selected from a post-acute residential rehabilitation programme and allocated to either a training or control group. Training comprised a 17-hour programme (across 8 weeks) with conversational interactions (i.e. structured and casual) between paid carers and people with TBI videotaped pre-training, post-training and at 6-months follow-up. Interactions were rated on the Adapted Measure of Support in Conversation (MSC), Adapted Measure of Participation in Conversation (MPC) and Global Impression Scales of conversation. MAIN OUTCOMES AND RESULTS:Trained paid carers were more able to acknowledge and reveal the competence of people with TBI. Conversations were perceived as more appropriate, interesting and rewarding compared to the control group. Improvements were confined to the structured conversation and were maintained for 6 months. CONCLUSIONS:Training paid carers has a positive effect on improving conversational interactions with people with TBI in a long-term care facility. These improvements can help to foster increased independence for the person with TBI in the home and community.
    背景与目标:
  • 【神经性贪食症在线讨论组: 患者之间基于互联网的交流的归纳方法。】 复制标题 收藏 收藏
    DOI:10.1002/eat.20542 复制DOI
    作者列表:Wesemann D,Grunwald M
    BACKGROUND & AIMS: OBJECTIVE:Online discussion forums are often used by people with eating disorders. METHOD:This study analyses 2,072 threads containing a total of 14,903 postings from an unmoderated German "prorecovery" forum for persons suffering from bulimia nervosa (www.ab-server.de) during the period from October 2004 to May 2006. The threads were inductively analyzed for underlying structural types, and the various types found were then analyzed for differences in temporal and quantitative parameters. RESULTS:Communication in the online discussion forum occurred in three types of thread: (1) problem-oriented threads (78.8% of threads), (2) communication-oriented threads (15.3% of threads), and (3) metacommunication threads (2.6% of threads). Metacommunication threads contained significantly more postings than problem-oriented and communication-oriented threads, and they were viewed significantly more often. Moreover, there are temporal differences between the structural types. CONCLUSION:Topics relating to active management of the disorder receive great attention in prorecovery forums.
    背景与目标:
  • 【为高级分子遗传学和生物化学领域的学生提供活动和评估解决方案,以在在线环境中指导和参与公共交流。】 复制标题 收藏 收藏
    DOI:10.1002/bmb.21389 复制DOI
    作者列表:Kanapeckas Métris KL
    BACKGROUND & AIMS: :Apart from classroom presentations to their instructors and peer groups, STEM students have limited opportunities or encouragement to engage in guided communication of scientific concepts to others (family, friends, or the general public). A critical need exists for accurate, comprehensible science to be disseminated to these groups. To develop student proficiency in communication of complex biomolecular concepts impacting diverse audiences, I introduce learning approaches and assessments easily adapted to fit the needs of individual instructors and any molecular biology or biochemistry laboratory or lecture course in a remote/online environment. To help students develop an appreciation of the needs of different audiences and the nuanced drivers of clear communication, I provided them the choice of projects of similar length: Option (1) Create a scientific news release and short podcast or video clip newscast describing a recent advancement in understanding the molecular/biochemical basis of a disease; or Option (2) Create a lesson plan and mini-video designed to teach a simple biochemical or molecular mechanism of disease with learning objectives, a brief activity, and appropriate assessment mechanisms. Students who chose the scientific news release/newscast activity distilled complex biomolecular concepts using the 5 W's of journalism-who, what, where, why, when-and learned to accurately communicate the relevance of advanced scientific discoveries and recent events for a broader audience. Students who chose the lesson plan designed activities centered on biomolecular science concepts that build upon what their audience already knows, revealing possibilities for undergraduates to contribute to educational outreach to secondary school teachers and classes.
    背景与目标: : 除了向教师和同伴小组进行课堂演讲外,STEM学生参与与他人 (家人,朋友或公众) 进行有指导的科学概念交流的机会或鼓励有限。迫切需要将准确,可理解的科学传播给这些群体。为了培养学生对影响不同受众的复杂生物分子概念的沟通能力,我介绍了易于适应的学习方法和评估,以适应个别讲师和任何分子生物学或生物化学实验室或远程/在线环境中的讲座课程的需求。为了帮助学生了解不同受众的需求以及清晰沟通的细微差别,我为他们提供了相似长度的项目选择: 选项 (1) 创建科学新闻发布和简短的播客或视频剪辑新闻广播,描述在理解疾病的分子/生化基础方面的最新进展; 或选项 (2) 创建课程计划和迷你视频,旨在教授具有学习目标的疾病的简单生化或分子机制,简短的活动和适当的评估机制。选择科学新闻发布/新闻广播活动的学生使用新闻业的5 w提炼了复杂的生物分子概念-谁,什么,为什么,什么时候-并学会了准确传达先进科学发现和最近事件的相关性更广泛的受众。选择课程计划的学生设计的活动以生物分子科学概念为中心,这些概念建立在听众已经知道的基础上,揭示了本科生为中学教师和班级的教育推广做出贡献的可能性。
  • 【基于导航仪的干预措施支持儿科重症监护病房的沟通: 一项初步研究。】 复制标题 收藏 收藏
    DOI:10.4037/ajcc2020478 复制DOI
    作者列表:Michelson KN,Charleston E,Aniciete DY,Sorce LR,Fragen P,Persell SD,Ciolino JD,Clayman ML,Rychlik K,Jones VA,Spadino P,Malakooti M,Brown M,White D
    BACKGROUND & AIMS: BACKGROUND:Communication in the pediatric intensive care unit (PICU) between families and the health care team affects the family experience, caregiver psychological morbidity, and patient outcomes. OBJECTIVE:To test the feasibility of studying and implementing a PICU communication intervention called PICU Supports, and to assess families' and health care teams' perceptions of the intervention. METHODS:This study involved patients requiring more than 24 hours of PICU care. An interventionist trained in PICU-focused health care navigation, a "navigator," met with parents and the health care team to discuss communication, decision-making, emotional, informational, and discharge or end-of-life care needs; offered weekly family meetings; and checked in with parents after PICU discharge. The feasibility of implementing the intervention was assessed by tracking navigator activities. Health care team and family perceptions were assessed using surveys, interviews, and focus groups. RESULTS:Of 53 families approached about the study, 35 (66%) agreed to participate. The navigator met with parents on 71% and the health care team on 85% of possible weekdays, and completed 86% of the postdischarge check-ins. Family meetings were offered to 95% of eligible patients. The intervention was rated as helpful by 97% of parents, and comments during interviews were positive. CONCLUSIONS:The PICU Supports intervention is feasible to implement and study and is viewed favorably by parents.
    背景与目标:
  • 【危险信号: 冠心病背景下的一系列临床医生-家庭沟通挑战。】 复制标题 收藏 收藏
    DOI:10.1017/S1047951116002730 复制DOI
    作者列表:Sekar P,Marcus KL,Williams EP,Boss RD
    BACKGROUND & AIMS: :We describe three cases of newborns with complex CHD characterised by communication challenges. These communication challenges were categorised as patient, family, or system-related red flags. Strategies for addressing these red flags were proposed, for the goal of optimising care and improving quality of life in this vulnerable population.
    背景与目标: : 我们描述了三例以沟通挑战为特征的复杂冠心病新生儿。这些沟通挑战被归类为患者,家庭或与系统相关的危险信号。提出了解决这些危险信号的策略,目的是优化护理并改善这一弱势群体的生活质量。
  • 【在大型军事医疗中心检查手术团队沟通的协议。】 复制标题 收藏 收藏
    DOI:10.1097/NNR.0000000000000462 复制DOI
    作者列表:Stucky CH,De Jong MJ,Kabo FW,Huffman SL
    BACKGROUND & AIMS: BACKGROUND:Preventable clinician communication errors are the most frequent root cause of surgical adverse events. Effective communication among surgical team members is an important overall indicator of clinical nursing excellence and is crucial to promote patient safety and reduce healthcare risk. OBJECTIVE:The purpose of this publication is to describe our research protocol, which will comprehensively investigate surgical team communication and surgical team structure. There are two overall study objectives: (a) to characterize the network factors that influence perioperative clinician communication and (b) to identify how team structure shapes communication effectiveness. Specifically, we will study the association among clinician relationships, surgical team familiarity, surgical team size, and communication effectiveness. METHODS:We will use an exploratory, prospective, cross-sectional, network-centric approach using social network analysis to determine how interdependent clinician relationships influence surgical communication patterns. Targeting an 80% response rate, we will use total population sampling to recruit all clinicians (nurses, surgeons, anesthetists, surgical technologists, students, residents) who directly provide surgical care in the operating room at a large military medical center. We will administer an electronic survey to surgical teams at the end of the surgical day to elicit clinician communication assessments and relational preferences. From the survey questions, we will develop six relational networks (interaction, close working relationship, socialization, advice seeking, advice giving, speaking up/voice) and three models that represent communication effectiveness for each participant and team. We will use various statistical methods to characterize the network factors that shape operating room clinician communication and identify how team structure shapes communication effectiveness. RESULTS:This study will start enrolling participants in 2020. DISCUSSION:We are among the first to comprehensively investigate operating room communication using social network analysis. The results of this study will provide valuable insight into nurse collaboration and communication in interprofessional teams, enable a thoughtful analysis of surgical staffing and perioperative team building, and inform future-targeted interventions to improve operating room communication weaknesses.
    背景与目标:
  • 【临终沟通的中国视角: 系统回顾。】 复制标题 收藏 收藏
    DOI:10.1136/bmjspcare-2019-002166 复制DOI
    作者列表:Pun JKH,Cheung KM,Chow JCH,Chan WL
    BACKGROUND & AIMS: BACKGROUND:Palliative care providers serving Chinese patients lack a culture-specific model of communication, a strong evidence base for this and clear guidance on its application. Thus, providers find it challenging to address patients' dignity, and determine their priorities and preferences for treatments and care, at the patients' final stage of life. AIM:This study explores the culture-specific influences and current understanding of end-of-life (EOL) communication in the Chinese context. METHODS:A qualitative systematic review of qualitative studies was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PsycINFO, PubMed and ERIC databases were searched for studies between January 1994 and July 2019, using keywords 'end of life', 'terminal care', 'communication' and 'Chinese'. Included studies were appraised with Critical Appraisal Skills Programme criteria. RESULTS:The search strategy yielded 982 entries and 13 studies were included. Six themes were identified in EOL communication in the Chinese context: (1) Chinese philosophies on the meaning of 'good death'. (2) Negative attitudes towards communication on dying. (3) EOL communication as a taboo topic. (4) Clinician-centred approaches to treatment-decision making. (5) Family expectations being prioritised over patient self-autonomy in prognosis disclosure. (6) Care-providers expressing puzzlement over cultural preferences regarding EOL communication. CONCLUSIONS:The review detailed the complexity of EOL communication in the Chinese context, urging for a communication model distinct from Western-based practices. Future research could explore a validated communication framework that addresses the local culture, thus enabling an understanding of patients' priorities and interpreting EOL encounters from a cross-cultural perspective.
    背景与目标:
  • 【全家?癌症幸存者与家人的沟通。】 复制标题 收藏 收藏
    DOI:10.1007/s10689-017-9987-8 复制DOI
    作者列表:Bowen DJ,Hay JL,Harris-Wai JN,Meischke H,Burke W
    BACKGROUND & AIMS: :Families often bear the burden of communication about cancer risk, as well as support during and after treatment for cancer in family members. These activities are left up to survivors and their families, with little support or knowledge of useful methods. We present data on aspects of family that are most relevant to risk of cancer-related communication and health promotion among family members. Families (a survivor, one first-degree relative and one parent; n = 313 families) were enrolled in the survey-based study. We assessed multiple aspects of family communication about risk for melanoma among family participants. Families communicate less frequently than desired about cancer risk. Most families do identify a "family health provider" who keeps family data and serves a resource for family members. The reasons given for lack of family communication are diverse but many can be addressed as part of a family communication intervention. Families are poised to improve their family communication about cancer risk and so can play a role in increasing the health of their members.
    背景与目标: : 家庭通常承担有关癌症风险的沟通负担,以及家庭成员在癌症治疗期间和之后的支持。这些活动由幸存者及其家人决定,很少支持或了解有用的方法。我们提供了与家庭成员之间与癌症相关的交流和健康促进风险最相关的家庭方面的数据。家庭 (一名幸存者,一名一级亲属和一名父母; N = 313个家庭) 被纳入了基于调查的研究。我们评估了家庭参与者中关于黑色素瘤风险的家庭沟通的多个方面。家庭就癌症风险进行交流的频率低于预期。大多数家庭确实确定了一个 “家庭保健提供者”,该提供者保存家庭数据并为家庭成员提供资源。缺乏家庭沟通的原因多种多样,但许多原因可以作为家庭沟通干预的一部分来解决。家庭准备改善他们关于癌症风险的家庭沟通,因此可以在增加成员的健康方面发挥作用。
  • 【使用宽带移动通信技术对救护车中的远程控制机器人远程回声系统进行现场测试。】 复制标题 收藏 收藏
    DOI:10.1007/s10916-008-9128-x 复制DOI
    作者列表:Takeuchi R,Harada H,Masuda K,Ota G,Yokoi M,Teramura N,Saito T
    BACKGROUND & AIMS: :We report the testing of a mobile Robotic Tele-echo system that was placed in an ambulance and successfully transmitted clear real time echo imaging of a patient's abdomen to the destination hospital from where this device was being remotely operated. Two-way communication between the paramedics in this vehicle and a doctor standing by at the hospital was undertaken. The robot was equipped with an ultrasound probe which was remotely controlled by the clinician at the hospital and ultrasound images of the patient were transmitted wirelessly. The quality of the ultrasound images that were transmitted over the public mobile telephone networks and those transmitted over the Multimedia Wireless Access Network (a private networks) were compared. The transmission rate over the public networks and the private networks was approximately 256 Kbps, 3 Mbps respectively. Our results indicate that ultrasound images of far higher definition could be obtained through the private networks.
    背景与目标: : 我们报告了对移动机器人远程回声系统的测试,该系统被放置在救护车中,并成功地将患者腹部的清晰实时回声成像传输到远程操作该设备的目的地医院。这辆车上的医护人员与在医院待命的医生之间进行了双向沟通。该机器人配备了超声探头,该探头由医院的临床医生远程控制,并以无线方式传输患者的超声图像。比较了通过公共移动电话网络传输的超声图像和通过多媒体无线接入网络 (专用网络) 传输的超声图像的质量。公共网络和专用网络上的传输速率分别约为256 Kbps,3 Mbps。我们的结果表明,可以通过专用网络获得更高清晰度的超声图像。
  • 【肠道定向催眠治疗炎症性肠病的可行性和可接受性: 简短交流。】 复制标题 收藏 收藏
    DOI:10.1080/00207140701506565 复制DOI
    作者列表:Keefer L,Keshavarzian A
    BACKGROUND & AIMS: :Hypnotically assisted treatments have been used to reduce stress, improve gastrointestinal motility, strengthen immune function, and potentially reduce inflammation. Such treatments may also help reduce disease flares and improve quality of life in inflammatory bowel diseases (IBD). The authors report the results of a case series of 8 white female patients with inactive IBD. All participants initiated and completed treatment, supporting the general acceptability of hypnotically assisted treatment among IBD patients. There was a significant improvement in IBD-quality of life scores for the group posttreatment, t(7) = -3.38, p = .01, with a mean improvement in quality of life of 29 points with significant changes in all 4 subscales. No negative effects of treatment were found.
    背景与目标: : 催眠辅助治疗已被用于减轻压力,改善肠胃蠕动,增强免疫功能,并可能减少炎症。这样的治疗也可能有助于减少疾病的爆发并改善炎症性肠病 (IBD) 的生活质量。作者报告了8例非活动性IBD的白人女性患者的病例系列结果。所有参与者开始并完成治疗,支持IBD患者普遍接受催眠辅助治疗。治疗后组IBD生活质量评分有显著改善,t(7) = -3.38,p = 0.01,生活质量平均改善29分,所有4个分量表均有显著变化。没有发现治疗的负面影响。

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