BACKGROUND:Central venous oxygen saturation (ScvO2) remains the gold standard surrogate for tissue oxygen extraction in paediatric cardiac surgery. Near-infrared spectroscopy (NIRS) has been developed as a non-invasive diagnostic tool for regional oxygen saturation. The aim was to compare regional oxygen saturation measured by NIRS with ScvO2 in postoperative paediatric cardiac patients. METHODS:In this prospective study, we included newborns and infants younger than 45 days undergoing heart surgery. We recorded continuous ScvO2 and NIRS regional saturation placed on the forehead (B) and right flank (S) for 48 h postoperatively. A Bland-Altman's analysis was used to assess the agreement between these measurements. RESULTS:A total of 23 patients were included with a median age of 12 days (2-46) and median weight of 3.1 kg (2.3-4.47). The mean difference (MD) ScvO2- B NIRS was 10.45% with limits of agreement (LOA) -17.23 to 38.13% and ScvO2- S NIRS MD 7.16% with LOA: -25.51 to 39.84%. The single ventricle ScvO2- S NIRS subgroup had MD within ± 5%; however, wide LOA was observed. The remaining subgroups showed MD nearly above ± 5%, with wide LOA. CONCLUSIONS:The regional oxygen saturation of brain and kidney did not match ScvO2 as estimation of global tissue perfusion. Nevertheless, NIRS may still provide information regarding regional circulation that may help in the management of neonatal cardiac surgery patients.

译文

背景:中央静脉血氧饱和度(ScvO2)仍然是小儿心脏外科手术中组织氧提取的金标准。近红外光谱法(NIRS)已被开发为一种用于区域血氧饱和度的非侵入性诊断工具。目的是比较由NIRS和ScvO2测得的小儿心脏术后患者的局部血氧饱和度。
方法:在这项前瞻性研究中,我们纳入了接受心脏手术的45天以下的新生儿和婴儿。我们记录了连续的ScvO2和NIRS区域饱和度放置在术后48 h的前额(B)和右胁(S)上。用布兰德-奥特曼(Bland-Altman)分析来评估这些测量之间的一致性。
结果:总共纳入23名患者,中位年龄为12天(2-46),中位体重为3.1 kg(2.3-4.47)。 ScvO2-B NIRS的平均差异(MD)为10.45%,协议限制(LOA)为-17.23至38.13%,Slovo2- S NIRS MD的7.16%LOA为-25.51至39.84%。单心室ScvO2-S NIRS亚组的MD≤±5%。但是,观察到广泛的LOA。其余亚组的MD值接近±5%,LOA较宽。
结论:脑和肾脏的局部血氧饱和度与ScvO2不符,无法估计整体组织灌注。尽管如此,NIRS仍可能提供有关区域循环的信息,这可能有助于新生儿心脏外科手术患者的管理。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录