BACKGROUND & AIMS: :Information on radiation accidents in China compiled by the health authorities was collected. About 468 accidents were reported in 1988-2004. Detailed data from 1988 to 1998 were analysed. As to the 332 accidents reported in 1988-98, 77.7% of the cases are related to lost sources, 84.64% are liability accidents and five persons died owing to the cases occurring in the application of gamma irradiators. It is essential to improve the data bank to manage radiation sources, and to make sure that the relevant laws, together with professional theory and technical knowledge, are disseminated well and learned by professionals.

背景与目标： : 收集了卫生当局汇编的中国辐射事故信息。1988-2004年报告了约468起事故。分析了1988年1998年的详细数据。至于1988-98年报告的332事故，77.7% 起案件与来源丢失有关，84.64% 起责任事故，5人因使用伽玛辐照器而死亡。必须改善数据库以管理辐射源，并确保相关法律以及专业理论和技术知识得到良好的传播和专业人员的学习。

BACKGROUND & AIMS: BACKGROUND:Sentinel surveillance of Keshan disease (KD) is limited by unable to give the prevalence rates and their estimates. This study was to find the national KD prevalence and the estimated patient numbers to provide evidence toward modifying the policy of KD prevention and control. METHOD:Using a probability proportional to population size, randomized, multistage, and cluster sampling, we surveyed 101,127, measured grain selenium levels; and surveyed household income with pre-designed questionnaires. RESULTS:The national prevalence rates of KD, chronic KD and latent KD were 2.21%, 0.50%, and 1.71% respectively. Chronic KD patients are mainly in the provinces where KD had been seriously epidemic. The KD prevalence rate was higher in females (2.20%) than in males (1.98%). These were also higher in older age groups. The cases younger than 30 years accounted for 13.6%, indicating the possibility that KD is still occurring. Nationally, the estimated numbers of KD and chronic KD patients are 1,675,500 (95% CI, 1,608,500-1,747,300) and 379,800 (95% CI, 346,700-412,800) respectively. Multiple logistic regression analysis indicated that family income was a significant dependent variable (OR: -0.258, 95% CI: -0.332 to -0.185, p<0.001). More than 2000 chronic KD patients found in the study were treated in 2009-2011. The limitation of this study was that sampling size was determined at national level. CONCLUSION:KD is still a public health issue among the people of the historically severe endemic areas. Selenium supplementation, self-management program for chronic KD patients and translation epidemiology of KD surveillance should be strengthened.

背景与目标：

BACKGROUND & AIMS: BACKGROUND:Paragonimiasis infection has no specific symptoms or typical radiologic findings, leading to the possibility of misdiagnosis. Thus, the objective of this study was to analyze clinical and radiological features, and treatment outcome of paragonimiasis in children in Southwest China to improve the awareness of this disease. METHODS:We retrospectively reviewed the records of children diagnosed with paragonimiasis in West China Second University Hospital between 2005 and 2016. The confirmed diagnosis of paragonimiasis was based on epidemiology history and seropositivity for paragonimiasis and/or detection of paragonimus eggs. Clinical, laboratory, and imaging findings of patients were examined in order to summarize risk factors, clinical characteristics, and treatment outcomes of these patients. RESULTS:A total of 123 patients were included; of them 112 (91.1%) lived in villages and 72 (58.5%) had a history of consuming freshwater crabs. Patients with paragonimiasis most frequently showed respiratory symptoms, including cough (26.0%, 32/123) and tachypnea (16.3%, 20/123), and gastrointestinal symptoms, including abdominal pain (26.8%, 33/123), abdominal distention (22.8%, 28/123), and vomiting (13.0%, 16/123). Laboratory examination showed elevated white blood cell (WBC) counts in the peripheral blood in 89 (72.4%) patients and eosinophilia in 102 (82.9%) patients. Tuberculosis (TB) coinfection was found in 4 (3.3%) patients. Main imaging findings included: effusions (90.4%), lymphadenopathy (40.4%), pulmonary ground-glass opacities (36.2%), cystic lesions (18.1%), and pleural thickening (17.0%). Twenty-nine patients (23.6%) received more than 1 course of praziquantel (PZQ). Additionally, 4 (19.0%) of 21 patients who were discharged from the hospital without complete treatment required rehospitalization for residual serous effusions. Moreover, patients from pericardial effusion group showed longer hospital stays and less elevated WBC counts than those from nonpericardial effusion group. CONCLUSION:Paragonimiasis should be considered in patients from endemic areas, especially in those with gastrointestinal and/or respiratory symptoms, elevated WBC count, eosinophilia, and serous effusions. Additionally, longer hospital stay may be necessary in cases of paragonimiasis associated with pericardial effusions.

背景与目标：

BACKGROUND & AIMS: :At present Chinese nurses could not get the up-to-date and high-quality evidences efficiently and conveniently due to language barrier and other practical difficulties. This program built a Chinese website of integrated evidence-based network information resources for EBN studies. Researchers hope to provide practical guidance and advice for nurses in non-English-speaking countries..

背景与目标： : 由于语言障碍和其他实际困难，目前中国护士无法有效，方便地获得最新，高质量的证据。该计划为EBN研究建立了一个基于证据的网络信息资源整合的中文网站。研究人员希望为非英语国家的护士提供实用的指导和建议。

BACKGROUND & AIMS: AIM:This article is a report of a study of occupational burnout among nurses in China. BACKGROUND:Burnout is described as feelings of emotional exhaustion, depersonalization and reduced personal accomplishment. It is well-known that burnout is a major problem for many professions. Nurses are considered to be particularly susceptible to this. Measuring burnout among nurses is important because their well-being has implications for stability in the healthcare workforce and for the quality of care provided. METHOD:The sample consisted of 495 nurses from three provincial hospitals in China. The Maslach Burnout Inventory -- General Survey (MBI-GS) was used to measure burnout, and the Occupational Stress Inventory -- Revised edition was used to measure two dimensions of occupational adjustment (occupational stress and coping resources). After statistical testing for validity and reliability of the MBI-GS with nurses in China, participants' scores were evaluated and analysed. RESULTS:Scores for burnout of surgical and medical nurses were statistically significantly higher than those of other nurses (P < 0.05). Lower educational status was associated with lower professional efficacy, and younger nurses reported higher levels of burnout. The most significant predictors of emotional exhaustion were role overload, responsibility, role insufficiency and self-care (P < 0.05). The most significant predictors of cynicism were role insufficiency, role boundary, responsibility and self-care (P < 0.05). The most significant predictors of professional efficacy were role insufficiency, social support and rational/cognitive coping (P < 0.05). CONCLUSION:It is important to reduce occupational stress in nurses and to strengthen their coping resources to prevent burnout. This could be achieved with job redesign, modification of shiftwork systems, and by offering occupational health education.

背景与目标：

BACKGROUND & AIMS: :Female entertainment workers (FEWs) in China are at increased risk of HIV and other sexually transmitted infections, but correlates of their risky sexual behaviour remain poorly understood. Using data from a series of four surveys, this paper employs repeated measures analysis to identify individual and social correlates of consistent condom use among FEWs in Shanghai. Results reveal that both individual cognitive and social influence factors are statistically significant in their bivariate relationships to consistent condom use with a stable or non-stable partner; only prevention motivation and perceived self-efficacy in condom use remain significant in the multiple regressions. When individual and social correlates are examined together, only peer support for condom use remains a significant and independent correlate of consistent condom use in sex with a non-stable partner. Behavioural intervention is urgently needed and should take a multilevel approach, emphasizing individual prevention motivation and behavioural skills training and promoting peer/social support.

背景与目标： : 中国的女性娱乐工作者 (few) 感染艾滋病毒和其他性传播感染的风险增加，但对其危险性行为的相关性仍知之甚少。本文利用四项调查的数据，采用重复措施分析，以识别上海few中持续使用安全套的个人和社会相关性。结果表明，个体认知和社会影响因素在与稳定或非稳定伴侣一致使用安全套的双变量关系中具有统计学意义; 在多元回归中，只有预防动机和安全套使用中的自我效能感仍然显着。当将个人和社会相关性一起检查时，只有同伴对避孕套使用的支持仍然是与不稳定伴侣在性行为中一致使用避孕套的重要且独立的相关性。迫切需要行为干预，并应采取多层次的方法，强调个人预防动机和行为技能培训，并促进同伴/社会支持。

BACKGROUND & AIMS: :The aims of this paper were to find out the status of HIV and syphilis infection and to examine the sexual behaviours between men who have sex with men only (MSM/M) and men who have sex with both men and women (MSM/W), as well as to determine the correlates for HIV and syphilis infection among MSM/M and MSM/W, respectively. Among 1693 MSM who participated in the study, the proportions of MSM/M and MSM/W were 82.1% and 17.9%, respectively. The prevalences of HIV infection were 7.0% in MSM/M and 6.6% in MSM/W and the prevalences of syphilis infection were 11.9% and 13.2%, respectively. Among the MSM/M subset, the correlates both for HIV and syphilis infection included having more sexual partners, and being receptive or both insertive and receptive for anal sex. Among the MSM/W subset, living in Chengdu was associated with HIV infection and using condoms inconsistently during anal sex was associated with syphilis infection. The findings of this survey call for interventions tailored according to the needs of different subsets of MSM.

背景与目标： : 本文的目的是了解艾滋病毒和梅毒的感染状况，并检查仅与男性发生性关系的男性 (MSM/M) 与与男性和女性发生性关系的男性 (MSM/W) 之间的性行为)，并分别确定MSM/M和MSM/W中HIV和梅毒感染的相关性。在参与研究的1693名MSM中，MSM/M和MSM/W的比例分别为82.1% 和17.9%。在MSM/M中7.0% HIV感染的患病率，在MSM/W中6.6%，梅毒感染的患病率分别为11.9% 和13.2%。在MSM/M子集中，与HIV和梅毒感染的相关性包括拥有更多的性伴侣，以及对肛交的接受性或插入性和接受性。在MSM/W亚组中，居住在成都与HIV感染有关，在肛交期间不一致使用避孕套与梅毒感染有关。这项调查的结果要求根据MSM不同子集的需求量身定制干预措施。

BACKGROUND & AIMS: BACKGROUND:This study provides a description and analysis of the development of occupational diseases in China as recorded in the official statistics during the period 2000-2010, identifies major challenges, and explores possible solutions for prevention and control. METHODS:In-depth textual analysis and data analysis of China's annual national reports of occupational diseases, as well as of corresponding policy and regulation documents. RESULTS:The number of recorded cases of occupational diseases increased rapidly in China between 2000 and 2010. Pneumoconiosis was the most prevalent category of occupational diseases. Chemical poisonings accounted for 13% of the cases of occupational diseases. CONCLUSIONS:Difficulties in diagnosis and inefficient surveillance are major impediments to the mitigation of occupational diseases. The new definition of occupational disease has provided an opportunity to enlarge the Catalogue of Occupational Diseases. Improved coordination of the different chemical regulations meant to protect human health may also facilitate the prevention of occupational disease.

背景与目标：

BACKGROUND & AIMS: :The carotenoids in the peel and flesh of 41 apricot cultivars were qualitatively and quantitatively analysed by UHPLC-APCI-MS/MS, and the L*, a*, b* and quality indexes of the fruits were determined. The results showed that the L*, a*, b* and quality indexes of the fruits were quite different, and 13 carotenoids were detected in the peel and flesh of apricots, among which ε-carotene, α-cryptoxanthin and apocarotenal were newly detected carotenoids in apricots. The total carotenoid content of the 41 apricot cultivars varied from 20.983 to 320.278 μg/g FW, and the total carotenoid content varied from 17.353 to 222.098 μg/g FW in the peel and from 2.536 to 98.179 μg/g FW in the flesh. The main components of apricot fruits were β-carotene and (E/Z)-phytoene, followed by β-cryptoxanthin and lutein. This study shows that carotenoids in apricot fruits have rich metabolic diversity.

背景与目标： : 用uhplc-apci-ms/MS对41个杏品种的果皮和果肉中的类胡萝卜素进行了定性和定量分析，测定了果实的L *，a *，b * 和品质指标。结果表明，果实的L *，a *，b * 和品质指标差异较大，在杏皮和果肉中检测到13种类胡萝卜素，其中 ε-胡萝卜素，α-隐黄质和apcarotenal是新检测到的。杏子中的类胡萝卜素。41个杏品种的总类胡萝卜素含量在20.983至320.278 μ g/g FW之间变化，果皮中的总类胡萝卜素含量在17.353至222.098 μ g/g FW之间变化，果肉中的总类胡萝卜素含量在2.536至98.179 μ g/g FW之间变化。杏果实的主要成分是 β-胡萝卜素和 (E/Z)-植物素，其次是 β-隐黄质和叶黄素。这项研究表明，杏果中的类胡萝卜素具有丰富的代谢多样性。

BACKGROUND & AIMS: BACKGROUND:While the cities in China in which spinal cord injury (SCI) studies have been conducted previously are at the forefront of medical care, northwest China is relatively underdeveloped economically, and the epidemiological characteristics of SCI have rarely been reported in this region. METHODS:The SCI epidemiological survey software developed was used to analyze the data of patients treated with SCI from 2014 to 2018. The sociodemographic characteristics of patients, including name, age, sex, and occupation, were recorded. The following medical record data, obtained from physical and radiographic examinations, were included in the study: data on the cause of injury, fracture location, associated injuries, and level of injury. Neurological function was evaluated using the American Spinal Injury Association (ASIA) impairment scale. In addition, the treatment and complications during hospitalization were documented. RESULTS:A total of 3487 patients with SCI with a mean age of 39.5 ± 11.2 years were identified in this study, and the male to female ratio was 2.57:1. The primary cause of SCI was falls (low falls 47.75%, high falls 37.31%), followed by traffic accidents (8.98%), and impact with falling objects (4.39%). Of all patients, 1786 patients (51.22%) had complications and other injuries. According to the ASIA impairment scale, the numbers of grade A, B, C, and D injuries were 747 (21.42%), 688 (19.73%), 618 (17.72%), and 1434 (41.12%), respectively. During the hospitalization period, a total of 1341 patients experienced complications, with a percentage of 38.46%. Among all complications, pulmonary infection was the most common (437, 32.59%), followed by hyponatremia (326, 24.31%), bedsores (219, 16.33%), urinary tract infection (168, 12.53%), deep venous thrombosis (157, 11.71%), and others (34, 2.53%). Notably, among 3487 patients with SCI, only 528 patients (15.14%) received long-term rehabilitation treatment. CONCLUSION:The incidence of SCI in northwest China was on the rise with higher proportion in males; fall and the MCVs were the primary causes of SCI. The occupations most threatened by SCI are farmers and workers. The investigation and analysis of the epidemiological characteristics of SCI in respiratory complications are important factors leading to death after SCI, especially when the SCI occurs in the cervical spinal cord. Finally, the significance of SCI rehabilitation should be addressed.

背景与目标：

BACKGROUND & AIMS: INTRODUCTION:There is growing attention to social mobility's impact on tobacco use, but few studies have differentiated the two conceptually distinct mechanisms through which changes in social class can affect tobacco smoking: the class status effect and the mobility effect. AIMS AND METHODS:I applied Diagonal Reference Modeling to smoking and heavy smoking among respondents of the 1991 China Health and Nutrition Survey who were revisited two decades later in 2011 (n = 3841, 49% male, baseline mean age was 38 years). I divided the sample into six social classes (non-employment, self-employed, owners, workers, farmers, and retirees) and measured social mobility by changes in income and occupational prestige. RESULTS:About 61.7% of men were smokers and those from the classes of workers, owners, and self-employees consumed more cigarettes compared to the unemployed, but women smokers (3.7%) tend to be from the lower classes (unemployed and farmers). Controlling for social class, each 1000 Yuan increase in annual income led to smoking 0.03 more cigarettes (p < .05) and 1% increase (p < .05) in the likelihood of heavy smoking among men, but the income effect is null for women. Upwardly mobile men (a 10-points surge in occupational prestige) smoked like their destination class (weight = 78%), whereas men with downward mobility were more similar to peers in the original class (weight = 60%). CONCLUSIONS:Contrary to the social gradient in smoking in other industrial countries, higher class status and upward mobility are each associated with more smoking among Chinese men, but not among women. IMPLICATIONS:Tobacco control policies should prioritize male smoking at workplaces and the instrumental purposes of using tobacco as gifts and social lubricant. Taxation may counter the surge in smoking brought by individuals' income increase after upward mobility. Caution should be paid to women joining the similar social gradient in smoking as they gain foothold in the labor market.

背景与目标：

BACKGROUND & AIMS: OBJECTIVE:To evaluate the clinical characteristics and laboratory test results in pregnant women with coronavirus disease 2019 (COVID-19). METHODS:A retrospective study to review and compare clinical data including electronic medical records and laboratory tests from pregnant and nonpregnant patients admitted the Central Hospital of Wuhan, China from December 8, 2019 to April 1, 2020. RESULTS:A total of 72 women (30 pregnant and 42 nonpregnant) with COVID-19 were included. No patients developed severe pneumonia during the study. Compared with the nonpregnant group, pregnant patients were admitted to hospital earlier (0.25 vs 11.00 days; P<0.001), presented milder symptoms, had a higher rate of asymptomatic infection (26.7% vs 0%), and shorter length of hospital stay (14.5 vs 17.0 days; P<0.01). Laboratory test results showed that levels of inflammation markers such as white blood cell count, neutrophil count and percentage, C-reactive protein, procalcitonin, and D-dimer were significantly higher in pregnant women, whereas mean lymphocyte percentage was significantly lower compared with nonpregnant women. CONCLUSION:In some respects, the clinical characteristics and laboratory test results of COVID-19 in pregnant patients seems to be distinctive from their nonpregnant counterparts. Appropriate advice and positive treatment might be critical to the prognosis when dealing with these pregnant patients. Pregnant patients with COVID-19 had their own positive clinical characteristics and special laboratory test results. Responsive medical advice and active treatment for those patients are critical to recovery.

背景与目标：

BACKGROUND & AIMS: :History of chronic lung diseases and household coal use for heating and cooking are established risk factors of lung cancer; however, few studies have been able to explore these risk factors simultaneously. Xuanwei, China, has some of the highest rates of lung cancer in China and most residents experience substantial in-home coal smoke exposures. Using a population-based case-control study of 498 lung cancer cases and 498 age-matched controls, we evaluated the risk of lung cancer in relation to coal smoke exposure and history of chronic lung diseases, including chronic obstructive pulmonary disease (COPD), asthma, tuberculosis (TB), chronic bronchitis, and emphysema. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by conditional logistic regression adjusting for potential confounders. We observed an increased risk of lung cancer with history of any chronic lung disease among males (OR = 14.2; 95%CI = 4.3-46.9), females (OR = 2.6; 95%CI = 1.1-6.3), smokers (OR = 12.7; 95%CI = 3.5-45.8), and nonsmokers (OR = 2.6; 95%CI = 1.1-6.4). Specifically, TB (OR = 83.7; 95%CI = 11.0-634.7), COPD (OR = 3.2; 95%CI = 1.7-6.0), and emphysema and chronic bronchitis (OR = 3.3; 95%CI = 1.7-6.4) were associated with increased risks. These findings suggest that history of chronic lung diseases may also increase risk of lung cancer in populations with indoor coal smoke exposures.

背景与目标： : 慢性肺部疾病史和家庭取暖和烹饪用煤是肺癌的危险因素; 然而，很少有研究能够同时探讨这些危险因素。中国宣威的肺癌发病率是中国最高的，大多数居民都有大量的家庭煤烟暴露。通过对498例肺癌病例和498年龄匹配的对照进行基于人群的病例对照研究，我们评估了与煤烟暴露和慢性肺部疾病 (包括慢性阻塞性肺疾病 (COPD)，哮喘，结核病 (TB)，慢性支气管炎，还有肺气肿。优势比 (ORs) 和95% 置信区间 (CIs) 通过条件logistic回归调整潜在混杂因素来计算。我们观察到男性 (OR = 14.2; 95% CI = 4.3-46.9)，女性 (OR = 2.6; 95% CI = 1.1-6.3)，吸烟者 (OR = 12.7; 95% CI = 3.5-45.8) 和不吸烟者 (OR = 2.6; 95% CI = 1.1-6.4)。具体而言，TB (OR = 83.7; 95% CI = 11.0-634.7)，COPD (OR = 3.2; 95% CI = 1.7-6.0)，以及肺气肿和慢性支气管炎 (OR = 3.3; 95% CI = 1.7-6.4) 与风险增加相关。这些发现表明，慢性肺部疾病的病史也可能增加室内煤烟暴露人群患肺癌的风险。

BACKGROUND & AIMS: BACKGROUND:Self-perception of uselessness is associated with increased mortality risk in older adults. However, it is unknown whether and to what extent changes in perceived uselessness are associated with mortality risk. METHODS:Using four waves of national longitudinal data of older adults from China (2005, 2008, 2011, and 2014), this study examines the association between changes in perceived uselessness and risk of subsequent mortality. Perceived uselessness is classified into three major categories: high levels (always/often), moderate levels (sometimes), and low levels (seldom/never). Five categories are used to measure change over three-year intervals: (1) persistently high levels, (2) increases to moderate/high levels, (3) persistent moderate levels, (4) decreases to moderate/low levels, and (5) persistently low levels. Cox proportional hazard models were used to estimate mortality risk associated with changes in levels of perceived uselessness. RESULTS:Compared to those with persistently low levels of perceived uselessness, those with persistently high levels of feeling useless had 80% increased hazard ratio (HR) in mortality [HR =1.80, 95% CIs: 1.57-2.08, p < 0.001]; and those with increasing levels, persistently moderate levels, and decreasing levels of perceived uselessness had 42% [HR = 1.42, 95% CIs: 1.27-159, p < 0.001], 50% [HR = 1.50, 95% CIs: 1.32-1.71, p < 0.001], and 23% [HR = 1.23, 95% CIs: 1.09-1.37, p < 0.001] increased hazard ratio in mortality, respectively, when background characteristics were taken into account. The associations were partially attenuated when socioeconomic, family/social support, behavioral, and health-related covariates were individually taken into account. Older adults with persistently high and moderate levels of perceived uselessness still exhibited significantly higher risks of mortality (16% [HR = 1.16, 95% CIs: 1.00-1.135, p < 0.05] and 22% [HR = 1.16, 95% CIs: 1.06-1.139, p < 0.015], respectively) after adjusting for all covariates, although no significant mortality risks were found for either increasing to moderate/high levels or decreasing to moderate/low levels of perceived uselessness. CONCLUSIONS:Persistently high and moderate levels of perceived uselessness are associated with significant increases in mortality risk. These findings have important implications for promoting successful aging in China.

背景与目标：

BACKGROUND & AIMS: :Re-emerging human adenovirus types 14 (Ad14) and 55 (Ad55) have caused severe respiratory diseases and even deaths during recent outbreaks. However, the seroprevalence of neutralizing antibodies (nAbs) in healthy adults, which may reflect previous circulation and help to predict potential outbreaks, remains unclear. In this study, we established micro-neutralizing (MN) assays on the basis of recombinant Ad14 and Ad55 reporter viruses, and we investigated serum nAbs in healthy blood donors from Southern China. We found that the overall seropositive rates were 24.8% and 22.4% for Ad14 and Ad55 nAbs, respectively. The seropositive rates were low in individuals younger than 20, and they gradually increased with age. Ad55-seropositive individuals tended to have high nAb titers (>1000), while low (72-200) and moderate (201-1000) nAb levels were frequently observed in Ad14-seropositive ones. Surprisingly, the seropositive rates and nAb levels were associated with the blood type but not the gender of the blood donors, with type AB individuals displaying higher seropositive rates and nAb levels. Interestingly, a significant positive correlation was observed between Ad14 and Ad55 seroprevalence, and higher titers of nAbs were detected in double-positive individuals compared to single-positive ones. These results clarified the human humoral immune responses against Ad14 and Ad55 and revealed a low level of herd immunity in some subpopulations, which emphasized the importance of monitoring these two highly virulent adenoviruses and reinforced the development of prophylactic vaccines.

背景与目标： : 重新出现的人类腺病毒14型 (Ad14) 和55型 (Ad55) 在最近的暴发中引起了严重的呼吸系统疾病，甚至死亡。然而，健康成年人中和抗体 (nAbs) 的血清阳性率可能反映了先前的循环并有助于预测潜在的爆发，目前尚不清楚。在这项研究中，我们基于重组Ad14和Ad55报告病毒建立了微中和 (MN) 检测方法，并研究了中国南方健康献血者的血清nAbs。我们发现Ad14和Ad55 nab的总体血清阳性率分别为24.8% 和22.4%。20岁以下的人的血清阳性率较低，并且随着年龄的增长而逐渐增加。Ad55-seropositive个体倾向于具有高nAb滴度 (>1000)，而在Ad14-seropositive个体中经常观察到低 (72-200) 和中等 (201-1000) nAb水平。令人惊讶的是，血清阳性率和nAb水平与血型有关，但与献血者的性别无关，而ab型个体的血清阳性率和nAb水平更高。有趣的是，在Ad14和Ad55血清阳性率之间观察到显着的正相关，与单阳性个体相比，在双阳性个体中检测到更高的nab滴度。这些结果阐明了针对Ad14和Ad55的人类体液免疫反应，并揭示了某些亚群中的群体免疫水平较低，这强调了监测这两种高毒性腺病毒的重要性，并加强了预防性疫苗的开发。