Ion Release and biocompatibility of a CaO-SrO-ZnO-SiO₂ (BT 101) based glass polyalkenoate cement (GPC) was compared against commercial GPCs, Fuji IX and Ketac Molar. The radiopacity (R) was similar for each material, 2.0-2.8. Ion release was evaluated on each material over 1, 7, 30 and 90 days. BT 101 release included Ca (23 mg/L), Sr (23 mg/L) Zn (13 mg/L), Si (203 mg/L). Fuji IX release includes Ca (0.7 mg/L), Al (3 mg/L) Si (26 mg/L), Na (60 mg/L) and P (0.5 mg/L) while Ketac Molar release includes Ca (1 mg/L), Al (0.6 mg/L) Si (23 mg/L), Na (76 mg/L) and P (0.7 mg/L). Simulated body fluid trials revealed CaP surface precipitation on BT 101. No evidence of precipitation was found on Fuji IX or Ketac Molar. Cytotoxicity testing found similar cell viability values for each material (~60 %, P = 1.000). Antibacterial testing determined a reduced CFU count with BT 101 (2.5 × 10³) when compared to the control bacteria (2.4 × 10⁴), Fuji IX (1.5 × 10⁴) and Ketac Molar (1.2 × 10⁴).

译文

:比较了CaO-SrO-ZnO-SiO 2(BT 101)基玻璃聚链烯酸酯水泥(GPC)与商业GPC,Fuji IX和Ketac Molar的离子释放和生物相容性。每种材料的射线不透性(R)相似,为2.0-2.8。在1、7、30和90天内评估每种材料的离子释放。 BT 101释放包括Ca(23 mg / L),Sr(23 mg / L),Zn(13 mg / L),Si(203 mg / L)。富士IX释放包含Ca(0.7 mg / L),Al(3 mg / L)Si(26 mg / L),Na(60 mg / L)和P(0.5 mg / L),而Ketac Molar释放包含Ca(1毫克/升),铝(0.6毫克/升),硅(23毫克/升),钠(76毫克/升)和磷(0.7毫克/升)。模拟的体液试验揭示了CaP表面在BT 101上的沉淀。在Fuji IX或Ketac Molar上未发现沉淀的迹象。细胞毒性测试发现每种材料的细胞生存力值相似(〜60%,P = 1.000)。与对照细菌(2.4×10 bacteria),富士IX(1.5×10⁴)和Ketac Molar(1.2×10⁴)相比,抗菌测试确定BT 101(2.5×10³)的CFU减少。

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