The aim of this study was to describe the pediatric population with ADHD and their pharmacological treatment. Using the Swedish National Patient Register and the Prescribed Drug Register we identified individuals below 19 years of age who were diagnosed or medically treated for ADHD for the first time 2006-2007. The unique patient identifiers were used to link information from the two registers to describe demographic characteristics, hospital care and drug treatments. Logistic regression model estimated the association between age, sex, frequency of hospitalization, diagnosis or treatment for other mental disorders and risk of gap in the treatment. Totally the study included 7931 patients of whom 74% were males. The mean age at first diagnosis was 12 years. Some 84% were medically treated for ADHD and approximately 90% received methylphenidate as the first substance. Combination therapy was rare and the most common combination was methylphenidate and atomoxetine. More than 55% of the patients, which could be followed up for two years after start of treatment, had at least one treatment gap of six months. Older age at diagnosis, lower number of hospitalizations and comorbidity with other mental disorders increased risks of gaps in medication. Approximately one fifth of the patients recorded in the National Patient Register as diagnosed with ADHD did not receive pharmacological treatment. Medication adherence seems to be low, when measured as gaps in treatment.

译文

这项研究的目的是描述患有ADHD的儿童人群及其药物治疗。使用瑞典国家患者登记册和处方药登记册,我们确定了2006-2007年首次诊断或接受ADHD治疗的19岁以下个体。唯一的患者标识符用于链接来自两个寄存器的信息,以描述人口统计学特征,医院护理和药物治疗。Logistic回归模型估计了年龄,性别,住院频率,其他精神障碍的诊断或治疗与治疗差距风险之间的关系。该研究总共包括7931名患者,其中74% 名是男性。首次诊断时的平均年龄为12岁。一些84% 接受了ADHD的医学治疗,大约90% 接受哌醋甲酯作为第一种物质。联合治疗很少见,最常见的联合是哌醋甲酯和阿托西汀。超过55% 的患者在开始治疗后可以随访两年,至少有一个治疗间隔为六个月。诊断时年龄较大,住院人数减少以及与其他精神障碍合并症增加了药物治疗差距的风险。在国家患者登记册中记录的诊断为ADHD的患者中,约有5分之1没有接受药物治疗。如果以治疗差距来衡量,药物依从性似乎很低。

+1
+2
100研值 100研值 ¥99课程
检索文献一次
下载文献一次

去下载>

成功解锁2个技能,为你点赞

《SCI写作十大必备语法》
解决你的SCI语法难题!

技能熟练度+1

视频课《玩转文献检索》
让你成为检索达人!

恭喜完成新手挑战

手机微信扫一扫,添加好友领取

免费领《Endnote文献管理工具+教程》

微信扫码, 免费领取

手机登录

获取验证码
登录