The duration of the QT interval is influenced by many pathologic processes and drugs. We report a 74-year-old man who was admitted after syncope. His electrocardiogram (ECG) showed a QT interval of 0.44 s (QTc 0.53 s). After 10 h a ruptured abdominal aortic aneurysm was diagnosed and the patient underwent implantation of an aorto-bi-iliac Y-prosthesis. After surgery QT interval normalized. Under therapy with amiodarone, given because of atrial fibrillation, QT prolongation occurred again and disappeared after discontinuation of amiodarone. The postoperative course was complicated by critical illness polyneuropathy and plexopathy. Whereas amiodarone is a well recognized cause of QT prolongation, aortic aneurysm rupture has not been described previously. Vegetative mechanisms and sudden decrease of cardiac afterload due to the ruptured aneurysm may have altered myocardial repolarisation and thus prolonged QT interval duration. In conclusion in a patient with syncope and QT prolongation, extracardiac causes like rupture or an aortic aneurysm have to be included into the differential diagnosis.

译文

QT间期的持续时间受许多病理过程和药物的影响。我们报告了一名74岁的男子,他在晕厥后入院。他的心电图 (ECG) 显示QT间隔为0.44 s (QTc 0.53 s)。10小时后,诊断出腹主动脉瘤破裂,患者接受了主动脉-双-Y假体的植入。手术后QT间期正常化。在胺碘酮治疗下,因房颤给予,QT延长再次发生,停用胺碘酮后消失。术后病程并发重症多发性神经病和神经丛病。尽管胺碘酮是QT延长的公认原因,但先前尚未描述主动脉瘤破裂。由于动脉瘤破裂而导致的营养机制和心脏后负荷的突然减少可能改变了心肌的复极化,从而延长了QT间期。总之,对于晕厥和QT间期延长的患者,必须将心脏外原因 (如破裂或主动脉瘤) 纳入鉴别诊断疾病。

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