肿瘤
词汇介绍
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解析
Metronomic /,mɛtrə'nɑmɪk/
释 义 adj. 节拍器的；有节奏的
例 句 Objective: To explore the role of metronomic therapy on treatment of advanced primary hepatocarcinoma . 目的：探索节拍疗法在晚期原发性肝癌治疗中的作用。
Chemotherapy 英 /,kiːmə(ʊ)'θerəpɪ; ,kem-/ 美 /,kimo'θɛrəpi/
释 义 n. [临床] 化学疗法
同根词 chemotherapeutic adj. 化学疗法的；chemistry n. 化学；化学过程；chemist n. 化学家；药剂师；chemiluminescence n. [化学] 化学发光，化合光；chemisorption n. [化学] 化学吸收作用；chemoreceptor n. 化学受体；[生理] 化学感受器（等于chemoceptor）；chemosynthesis n. [化学] 化学合成；chemisorb vt. 用化学方法吸收；用化学方法吸附
例 句 If any cancer remains in the abdomen or chest after chemotherapy, it can be treated with an operation to remove your lymph glands . 如果任何癌症在化疗后仍然存在于腹部或胸部，可以通过手术切除淋巴结来治疗。
概述
复制标题转移性结直肠癌患者一线诱导后贝伐单抗或贝伐单抗联合节拍化疗维持治疗的II期随机研究: MOMA试验
发表时间：2019-03-01
影响因子：6.7
作者： Chiara Cremolini
期刊：Eur. J. Cancer
MOMA (Maintenance bevacizumab Only or bevacizumab plus Metronomic chemotherapy in Advanced colorectal cancer) was a prospective, open-label, multicentre, comparative, randomised phase II study including mCRC patients recruited at 16 Italian Oncology Units. Main inclusion criteria were histologically confirmed colorectal adenocarcinoma; age between 18 and 75 years; Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-2 if age≤70 years, or 0 if age 71-75 years; unresectable and measurable metastatic disease according to RECIST, version 1.1 and adequate bone marrow, hepatic and renal function. Main exclusion criteria were previous palliative chemotherapy or biologic therapy for mCRC; adjuvant treatment with oxaliplatin completed less than 12 months before relapse; adjuvant treatment with fluoropyrimidine monotherapy completed less than 6 months before relapse and peripheral neuropathy of grade 2 or higher according to common terminology criteria for adverse events (CTCAE), version 4.0.
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