肿瘤
词汇介绍
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解析
Allogeneic 英 /,ælə(ʊ)dʒɪ'niːɪk; -dʒɪ'neɪɪk/ 美 /,ælədʒɪ'niɪk/
释 义 adj. 同种异体的;同种异系的
同根词 allogamous adj. [植] 异体受精的;[植] 异花受粉的;allogamy n. 异体受精,异花受粉;allograft n. [病理] 同种异体移植物
例 句 Conclusions: Percutaneous injection of autologous bone marrow and allogeneic bone powder appears to be an effective and simple method for unicameral bone cysts. 结论:经皮注射自体骨髓加异体骨粉移植治疗单房性骨囊肿是一种简单、微创、疗效确切的方法。
Stem 英 /stem/ 美 /stɛm/
释 义 n. 干;茎;船首;血统;vt. 阻止;除去…的茎;给…装柄;vi. 阻止;起源于某事物;逆行
同根词 stemmed adj. 去掉茎或梗的;有茎或梗的;装有…柄的;stemless adj. 无茎的;无梗的;stemmer n. 抽梗机,除梗器;抽梗工人;stemmed v. 起源于(stem的过去分词形式);除去…的茎;给(假花等)装梗
例 句 But the flow from the stem tip prevents them from doing this. 但是,来自主干顶端的(激素)流会阻止它们这么做。
Transplantation 英 /,trænsplɑːn'teɪʃən/
释 义 n. 移植;迁移;移民
同根词 transplantable adj. 可移植的,可移种的;transplant n. 移植;移植器官;被移植物;移居者;transplanter n. 移植机;移植者;transplant vi. 移植;迁移;移居;transplant vt. 移植;迁移;使移居
例 句 This involves transplantation of the organ from one person to another person, often to replace a non-functional organ in the latter. 它包括从一个个体到另一个个体的器官移植,往往是为了取代后者失去功能的某个器官。
概述
半相合与无关异基因干细胞移植治疗首次完全缓解的急性淋巴细胞白血病: 代表EBMT的ALWP
发表时间:2019-08-19
影响因子:9.9
作者: Noga Shem-Tov
期刊:Leukemia
Unmanipulated haploidentical allogeneic stem cell transplantation (Allo-SCT) has become an attractive alternative for patients lacking HLA-matched sibling or unrelated donors. However, data of outcome in ALL is still scarce. The outcomes of 1234 adult patients with ALL in first complete remission (CR1) who underwent Allo-SCT between 2007 and 2016 were analyzed. Comparison was done between haploidentical donor (Haplo) (136 patients), matched unrelated donor (MUD 10/10) (809 patients), and mismatched unrelated donor (MMUD 9/10) (289 patients). Univariate analysis showed similar outcomes in Haplo, MUD, and MMUD, including OS, LFS, RI, NRM, AGVHD, and CGVHD. In multivariate analysis, Haplo was not associated with worse outcomes compared to MUD 10/10 and MMUD 9/10. Indeed, compared to Haplo, the hazard ratio (HR) for LFS, OS, RI, NRM, AGVHD, and CGVHD were 1.1 (p = 0.7), 0.9 (p = 0.4), 1.35 (p = 0.2), 0.7 (p = 0.2), 1.1 (p = 0.8), and 0.8 (p = 0.2) for MUD, respectively, and 1.1 (p = 0.8), 1.0 (p = 1.0), 1.2 (p = 0.3), 0.8 (p = 0.4), 1.2 (p = 0.3), and 0.9 (p = 0.6) for MMUD, respectively.
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