Dysplasia 英 /dɪs'pleɪzɪə/
释 义 n. 发育不良；发育异常；异常结构；异型增生；不典型增生
例 句 Objective: To investigate the relationship between gonad dysplasia and abnormal chromosome karyotypes. 研究目的：研究性腺发育异常与染色体异常的相关性。
作者： Remi Mahmoud
期刊：Clin. Gastroenterol. Hepatol
We conducted a retrospective cohort analysis of patients with IBD undergoing colonoscopic surveillance between January 2001-December 2017 at a tertiary IBD referral center (The Mount Sinai Hospital (MSH), New York, NY, United States of America). Eligible patients were identified as described previously. Inclusion criteria were: an endoscopically and histologically confirmed diagnosis of IBD (Crohn’s disease [CD], ulcerative colitis [UC] or IBD-unclassified [IBD-U]); at least left-sided colonic involvement (UC patients, Montreal classification E2 or E3) or >30% involvement of colonic mucosa (CD, IBD-U); disease duration of > 8 years, or any disease extent or duration in patients with concomitant PSC; an “index” surveillance colonoscopy (defined below) that was followed at least 3 months later by a procedure that allowed for colonic histologic assessment (i.e. at least one subsequent surveillance colonoscopy or colectomy specimen, or any type of procedure yielding a diagnosis of IND or CRN) and; histology analyzed by specialized IBD pathologists at MSH. Patients were excluded if ACRN or colectomy occurred prior to or within 3 months of the index colonoscopy. Patients with a history of IND or LGD prior to the index colonoscopy (henceforth referred to as “prior dysplasia”) were not excluded.