Practice patterns of image guided particle therapy in Europe: A 2016 survey of the European Particle Therapy Network (EPTN)复制标题

欧洲图像引导粒子治疗的实践模式: 欧洲粒子治疗网络 (EPTN) 的2016调查

In radiation therapy, ‘image guidance’ is a general term ensuring the visualization and quantification of geometric uncertainties caused by the treatment setup or changing anatomy of the patient prior to or during a treatment fraction. For particle therapy, a detailed understanding of intra- and inter-fractional changes is essential for determining internal treatment margins and optimizing beam parameters in order to achieve greater accuracy and precision of radiation delivery. Moreover, the imaging requirements for the treatment of moving targets using particles are more stringent than for photons, as it is not only important to monitor positional changes of the tumour and/or normal tissues relative to the isocentre, but also morphological changes in the beam path need to be checked. Small positional variations can moreover lead to a significantly larger dose degradation in particle therapy than in photon therapy. This degradation might not always be compensated for by a correction of the isocentre, but may require treatment plan adaptation.

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