肿瘤
词汇介绍
拓展阅读
解析
Pemetrexed
释 义 n. 培美曲塞
例 句 Maintenance therapy with the drug pemetrexed improves the survival of people with non-small-cell lung cancer whose disease has not progressed after chemotherapy, a new study has found. 一项新的研究发现,使用培美曲塞药物进行的保守治疗,可以非小细胞肺癌患者的存活率,且在化疗之后疾病没有进展。
概述
Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer复制标题
奥西替尼或铂类-培美曲塞治疗EGFR T790M-Positive肺癌
发表时间:2017-02-16
影响因子:70.7
作者: T.S. Mok
期刊:N. Engl. J. Med
The median duration of progression-free survival was significantly longer with osimertinib than with platinum therapy plus pemetrexed (10.1 months vs. 4.4 months; hazard ratio; 0.30; 95% confidence interval [CI], 0.23 to 0.41; P<0.001). The objective response rate was significantly better with osimertinib (71%; 95% CI, 65 to 76) than with platinum therapy plus pemetrexed (31%; 95% CI, 24 to 40) (odds ratio for objective response, 5.39; 95% CI, 3.47 to 8.48; P<0.001).
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