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首页 > 医学词汇大全 > percutaneous ethanol injection
percutaneous ethanol injection

肿瘤

关键词肿瘤 手术操作 肝癌

词汇介绍

拓展阅读

解析

Percutaneous   英 /ˌpɜːkjuːˈteɪniəs/   美 /ˌpɜːrkjuːˈteɪniəs/  

释    义   adj. 经皮的;经由皮肤的

例    句   The main cause of infection in occupational settings is exposure to HIV-infected blood via a percutaneous injury (i.e. from needles, instruments, bites which break the skin, etc.). 在职业环境中受到感染的主要原因是,皮肤上伤口的血液(如由针,医疗器械,或叮咬而造成的皮肤破损)暴露于HIV病毒污染中。

 

Ethanol   英 /ˈeθənɒl/   美 /ˈeθənɔːl,ˈeθənoʊl/

释    义   n. [有化] 乙醇,[有化] 酒精

例    句   But the significance of the quarrel goes well beyond ethanol. 但是这场争吵的意义却远远超出乙醇的范围。

 

Injection   英 /ɪnˈdʒekʃn/   美 /ɪnˈdʒekʃn/

释    义   n. 注射;注射剂;充血;射入轨道

同根词   injectable adj. 可注射的

               injector n. 注射器;注射者;注水器

               injectable n. 血管注射剂

               inject vt. 注入;注射

例    句   In these experiments, which have yet to be published, he uses an antibiotic injection to knock out the hair cells devoted to balance. 他在这些尚在整理出版的试验中,使用了一种抗生素注射剂来破坏保持平衡的毛细胞。

概述

肝癌是最常见的恶性肿瘤之一,其病死率位居恶性肿瘤的前几位,目前手术切除是治疗肝癌的主要方法,对于大多数肝癌患者当确诊时,限于肿瘤的位置、大小、多个病灶、肝功能及全身情况而无法耐受手术等原因,根治性切除已无法进行,经皮无水乙醇注射疗法(PEI)是目前无法手术切除肝癌的一种较为安全可靠的治疗方法。   经皮无水乙醇注射治疗,1983年杉浦等对实验性小鼠肝癌灶注射无水乙醇治疗获得成功,1983年Livraghi报道了临床应用无水乙醇治疗小肝癌后,

Efficacy and Safety of Ablative Therapy in the Treatment of Patients with Metastatic Pheochromocytoma and Paraganglioma复制标题

消融治疗转移性嗜铬细胞瘤和副神经节瘤的疗效和安全性

发表时间:2019-02-07

影响因子:6.2

作者: Jacob Kohlenberg

期刊:Cancers (Basel)

Metastatic pheochromocytoma and paraganglioma (PPGL) are incurable neuroendocrine tumors. The goals of treatment include palliating symptoms and reducing tumor burden. Little is known about the use of radiofrequency ablation (RFA), cryoablation (CRYO), and percutaneous ethanol injection (PEI) to treat metastatic PPGL. We performed a retrospective study of patients age 17 years and older with metastatic PPGL who were treated with ablative therapy at Mayo Clinic, USA, between June 14, 1999 and November 14, 2017. Our outcomes measures were radiographic response, procedure-related complications, and symptomatic improvement. Thirty-one patients with metastatic PPGL had 123 lesions treated during 42 RFA, 23 CRYO, and 4 PEI procedures. The median duration of follow-up was 60 months (range, 0-163 months) for non-deceased patients. Radiographic local control was achieved in 69/80 (86%) lesions. Improvement in metastasis-related pain or symptoms of catecholamine excess was achieved in 12/13 (92%) procedures. Thirty-three (67%) procedures had no known complications. Clavien-Dindo Grade I, II, IV, and V complications occurred after 7 (14%), 7 (14%), 1 (2%), and 1 (2%) of the procedures, respectively. In patients with metastatic PPGL, ablative therapy can effectively achieve local control and palliate symptoms.

译文

转移性嗜铬细胞瘤和副神经节瘤是不可治愈的神经内分泌肿瘤。治疗目标包括缓解症状和减轻肿瘤负担。目前对射频消融术(RFA)、冷冻消融术(CRYO)和经皮乙醇注射(PEI)治疗转移性PPGL的应用知之甚少。 我们对1999年6月14日至2017年11月14日在美国梅奥诊所接受消融治疗的17岁及以上转移性PPGL患者进行了回顾性研究。我们的结果是影像学反应、手术相关并发症和症状改善。31例转移性PPGL患者在42次RFA、23次冷冻和4次PEI手术中共治疗了123个病灶。中位随访时间为60个月(0-163个月)。 69/80(86%)病灶行x线局部控制。转移相关疼痛或儿茶酚胺过量症状的改善在12/13(92%)手术中实现。33例(67%)手术没有已知的并发症。clavein-Dindo一级、二级、四级和五级并发症分别发生在7例(14%)、7例(14%)、1例(2%)和1例(2%)手术后。对于转移性PPGL患者,消融治疗能有效地达到局部控制和缓解症状的目的。