释 义 n. 贝伐单抗
例 句 Causes of death were predominantly due to lung cancer, but 14 patients in the bevacizumab group and 2 in the control group died as a result of drug toxicity. 尽管导致患者死亡的原因主要是肺癌，但是贝伐单抗组的14名患者以及对照组的2名患者却死于药物毒性。
作者： Florence Baettig
期刊：J Immunother Cancer
Treatment options for advanced cervical cancer are limited and patients experiencing recurrence after first-line cisplatin-based chemotherapy and bevacizumab have a poor prognosis. A recent phase II study in advanced cervical cancer has demonstrated a disease control rate of 68.4% with the immune checkpoint inhibitor nivolumab. By blocking immune checkpoints, immunotherapy puts the immune system into a state of hyper-activation that can cause immune-related adverse events. We present the clinical, pathological and molecular data of a patient with metastatic cervical cancer and progressive disease after second-line therapy. We report on the therapeutic response under third-line immunotherapy with nivolumab, the immune-related adverse events (IRAE), and their successful management.