Interleukin 英 /ɪn'tə'lʊkɪn/ 美 /ɪn'tə'lʊkɪn/
释 义 n. [生化] 白介素
例 句 To observe the effect of mizolastine on leukotriene B4(LTB4) and interleukin 5(IL 5) released by spleen lymphocytes of allergic mice challenged by ovalbumin(OVA). 观察咪唑斯汀对卵蛋白（OVA）致敏的小鼠脾淋巴细胞释放白三烯B4（LTB4）和白介素5（IL 5）的影响。
作者： Ryoichi Iwata
Accumulating evidence suggests that the stem-like properties of GBM sphere cells (GSCs) contribute to therapeutic resistance in GBM. In general, GBM cells create an immunosuppressive microenvironment and employ various molecular and cellular alterations to escape immune surveillance. Wei et al. have recently shown that GSCs are powerful mediators of immunosuppression of the adaptive immune system, specifically T-cell responses. A recent advance in GBM biology has divided GSCs into two subtypes, with the mesenchymal (MES) GSC population as the more malignant subtype. Proneural (PN) GSCs, on the other hand, induce significantly stronger transforming growth factor-β-mediated suppression of CD8+ T cells and natural killer (NK) cells. Interleukin (IL)-10 is a common prognostic marker in GBM. However, the underlying molecular mechanisms that regulate IL-10 production are poorly understood.