释 义 n. 一种选择性的G9a组蛋白甲基转移酶抑制剂
例 句 In this study, we have analyzed the dynamics and possible role of histone H3K9 methylation, a major repressive modification, as well as the effects on microspore embryogenesis initiation of BIX-01294, an inhibitor of histone methylation, tested for the first time in plants, in Brassica napus and Hordeum vulgare.在本研究中，我们分析了组蛋白H3K9甲基化的动态和可能的作用，以及BIX-01294对小孢子胚胎发生起始的影响，BIX-01294是组蛋白甲基化的抑制剂，这是首次在植物、甘蓝型油菜和大麦中进行了检测。
作者： Jang JE
期刊：J Exp Clin Cancer Res
Methods: We evaluated the effects of G9a inhibition on the unfolded protein response and autophagy in AML and LSC-like cell lines and in primary CD34+CD38- leukemic blasts from patients with AML and investigated the underlying mechanisms. The effects of treatment on cells were evaluated by flow cytometry, western blotting, confocal microscopy, reactive oxygen species (ROS) production assay.