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Thyroid Adenoma

儿科

关键词儿科 临床研究术语 肿瘤

词汇介绍

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解析

thyroid 英 /ˈθaɪrɔɪd/  美 /ˈθaɪrɔɪd/

释    义   n. 甲状腺;甲状软骨;甲状腺剂     

adj. 甲状腺的;盾状的

例    句   If absorbed through contaminated food, especially milk and milk products, it will accumulate in thethyroid and cause cancer. 如通过污染食物,特别是牛奶和奶制品吸收,它会积聚在甲状腺上并引起癌症


adenoma 英 /,ædɪ'nəʊmə/  美 /,ædə'nomə/

释    义   n. [肿瘤] 腺瘤

例    句   The accuracy of diagnosis for thyroid adenoma and nodular goiter by color Doppler were 90% and81% respectively. 彩色多谱勒对甲状腺腺瘤及结节性甲状腺肿的诊断正确率90%和81%。

概述

甲状腺良性肿瘤病理上可分为滤泡状和乳头状囊性腺瘤两种,前者较常见。腺瘤周围有完整的包膜,其临床表现,多见于40岁以下的妇女。腺瘤多为单发,呈圆形或椭圆形,局限在一侧腺体内。质地较周围甲状腺组织稍硬,表面光滑,无压痛,能随吞咽上下移动。腺瘤生长缓慢,大部分患者无任何症状。乳头状囊性腺瘤有时可因囊壁血管破裂而发生囊内出血,此时,肿瘤体积可在短期内迅速增大,局部出现胀痛。分类①滤泡性腺瘤:嗜酸性腺瘤、伴有乳头状增生的滤泡性腺瘤、胎儿性腺瘤肿瘤、印戒细胞型滤泡性腺瘤、黏液型滤泡性腺瘤、脂肪腺瘤、透

Future of Theranostics: An Outlook on Precision Oncology in Nuclear Medicine复制标题

核医学中精准肿瘤学的未来

发表时间:2019-09-04

影响因子:7.4

作者: Langbein Thomas

期刊:J Nucl Med

Molecular alterations in malignant disease result in the expression or upregulations of various targets that can be used for imaging and treatment with radiopharmaceuticals. This theranostic principle has acquired greater importance in personalized medicine in recent years, particularly in oncology, where advanced tumors can be treated effectively with low side effects. Since the pioneering use of I in differentiated thyroid cancer in the 1940s, remarkable achievements in nuclear medicine endoradiotherapy have been demonstrated, mainly in the treatment of neuroendocrine neoplasms by using Lu-labeled somatostatin analogs or in the treatment of advanced prostate cancer using prostate-specific membrane antigen-directed radionuclide therapy.

译文

恶性疾病的分子改变导致各种靶点的表达或上调,这些靶点可用于放射药物的成像和治疗。近年来,这一治疗原则在个体化医疗中获得了更大的重要性,特别是在肿瘤领域,在肿瘤领域,晚期肿瘤可以有效治疗,且副作用小。自20世纪40年代I在分化型甲状腺癌中的首次应用以来,在核医学内放射治疗方面取得了显著的成就,主要用于lu标记生长抑素类似物治疗神经内分泌肿瘤或前列腺特异性膜抗原导向放射性核素治疗晚期前列腺癌。