myasthenia 英 /,maɪəs'θiːnɪə/ 美 /,maɪəs'θinɪə/
释 义 n. [内科] 肌无力；肌肉衰弱
例 句 Emergency thymectomy is the treatment of choice for crisis of myasthenia gravis. 外科手术是治疗重症肌无力危象的方法之一。
作者： Zuercher Adrian W
Finally, Fc and FcγR-targeting therapeutics, comprise molecules that target the Fc of IgG, such as the recombinant soluble FcγIIb receptor valziflocept (SM101/SHP652) and various monoclonal antibodies directed against the receptors. The developmental status of these three classes of molecules ranges from preclinical to ongoing phase 3 clinical studies. Efgartigimod and rozanolixizumab are the most advanced and have demonstrated encouraging results from phase 2 trials in immune thrombocytopenia and myasthenia gravis. Although initial results are promising, further long-term data and a better understanding of the unique mechanisms of action of the different molecules are needed. The efficacy, safety, convenience of administration, duration of effects, and cost will all contribute to determining which of the molecules will be successful in the clinic.