摘要

Remission in thrombotic thrombocytopenic purpura (TTP) was achieved in two patients after repeated exchange transfusion. Since both patients had renal insufficiency, exchange was performed with hemodialysis. This provided optimal volume control and facilitated the rapid exchange of blood. The infusion of plasma did not maintain the clinical improvement achieved with exchange transfusion. Until a concentrate of the putative factor deficient in TTP becomes available, an exchange procedure remains the most expeditious method for the replacement of any deficient factor. The procedure of hemodialysis can be adapted to perform exchange transfusion safely and efficiently.

译文

两名患者经过反复换血后，血栓性血小板减少性紫癜 (TTP) 获得缓解。由于两个病人都有肾功能不全，所以用血液透析进行交换。这提供了最佳的容量控制和促进血液的快速交换。血浆的输注并不能维持交换输注所取得的临床改善。在 TTP 缺乏的假定因素集中可用之前，交换程序仍然是替代任何缺乏因素的最快捷的方法。血液透析程序可以适应安全有效地进行换血。