摘要

We conducted a retrospective seroepidemiological study to evaluate the relationship between past chlamydial infection and primary fallopian tube carcinoma (PFTC). Postoperative serum samples were drawn from 79 consecutive patients treated for PFTC in 1985-2000. For each case two controls were selected. Serum samples were analysed for IgG antibodies to different C. trachomatis serotype pools and to C. pneumoniae. Seropositivity in general or serum antibody levels to different C. trachomatis serovars or C. pneumoniae did not differ between PFTC patients and controls. The lack of association between anti-chlamydial antibodies and PFTC suggests that past chlamydial infection does not play a role in the etiopathogenesis of PFTC. However, because chlamydial infection is common at young age and PFTC develops decades later, we cannot definitively exclude the possibility that C.trachomatis contributes to the development of PFTC.

译文

我们进行了一项回顾性血清流行病学研究,以评估过去衣原体感染与原发性输卵管癌 (PFTC) 之间的关系。术后血清样本取自 1985年至 2000 间连续 79 例接受 PFTC 治疗的患者。对于每种情况,选择两个对照。分析血清样本中不同沙眼梭菌血清型和肺炎梭菌的 IgG 抗体。一般血清阳性或不同沙眼梭菌血清抗体水平或肺炎梭菌在 PFTC 患者和对照组之间没有差异。抗衣原体抗体和 PFTC 之间缺乏关联表明过去的衣原体感染在 PFTC 的病因中没有发挥作用。然而,由于衣原体感染在年轻时很常见,几十年后 PFTC 发展,我们不能明确排除沙眼衣原体感染导致 PFTC 发展的可能性。

Chlamydial Infection

儿科 衣原体感染 疾病
概述  :  

 新生儿衣原体感染是由沙眼衣原体(CT)引起。衣原体是必须在活细胞内生活、增殖的一类独立微生物群,其中与新生儿感染有关的主要是CT。本病主要通过性传播,是发达国家最常见的性传播疾病。新生儿CT感染主要是在分娩时通过产道获得,剖宫产出生的婴儿受感染的可能性很小,多由胎膜早破病原体上行而致。 临床表现 ① 衣原体结膜炎:是新生儿期结膜炎中最常见的病原菌,暴露于病原体者有1/3发病,潜伏期通常为5-14天,很少超过19天。胎膜早破患儿可更早出现结膜炎。分泌

chlamydial  /kləˈmɪdɪəl/

       adj. 衣原体的

       For example, 10 - 40% of women with untreated chlamydial infection develop symptomatic pelvic inflammatory disease. 在沙眼衣原体感染未得到治疗的女性中,有10-40%的人发展为症状性盆腔炎症。

 

infection  /ɪn'fekʃ(ə)n/  /ɪn'fɛkʃən/

       n. 感染;传染;影响;传染病

       In women chlamydial infection is one of the principal causes of Pelvic inflammatory disease.  在妇女沙眼衣原体感染是其中一个主要的原因,盆腔炎的。

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