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Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea.
口腔下颌前移装置和持续气道正压通气治疗阻塞性睡眠呼吸暂停-低血压随机对照试验的荟萃分析。
Continuous positive airway pressure Mandibular advancement device Meta-analysis Obstructive sleep apnoea-hypopnoea
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摘要

Obstructive sleep apnoea-hypopnoea (OSAH) causes excessive daytime sleepiness, impairs quality-of-life, and increases cardiovascular disease and road traffic accident risks. Continuous positive airway pressure (CPAP) treatment and mandibular advancement devices (MAD) have been shown to be effective in individual trials but their effectiveness particularly relative to disease severity is unclear. A MEDLINE, Embase and Science Citation Index search updating two systematic reviews to August 2013 identified 77 RCTs in adult OSAH patients comparing: MAD with conservative management (CM); MAD with CPAP; or CPAP with CM. Overall MAD and CPAP significantly improved apnoea-hypopnoea index (AHI) (MAD -9.3/hr (p 

译文

阻塞性睡眠窒息-睡眠不足 (OSAH) 会导致白天过度嗜睡,损害生活质量,并增加心血管疾病和道路交通事故的风险。持续气道正压通气 (CPAP) 治疗和下颌前移装置 (MAD) 已在个别试验中被证明是有效的,但它们的有效性,特别是与疾病严重程度相关的效果尚不清楚。一项 MEDLINE 、 Embase 和科学引文索引搜索更新了 2013年8月的两个系统综述,在成年 OSAH 患者中确定了 77 个随机对照试验,比较: MAD 与保守治疗 (CM); MAD 与 CPAP; 或 CPAP 与 CM。总体来说,MAD 和 CPAP 显著改善了呼吸暂停-低血压指数 (AHI) (MAD-9.3/hr (p

Continuous positive airway pressure

儿科 呼吸系统 治疗方法
概述  :  

无创持续气道正压通气(NCPAP)是在自主呼吸条件下,经鼻塞或面罩等方式提供一定的压力水平,使整个呼吸周期内气道均保持正压的通气方式。 应用指征 临床上出现以下情况时可考虑使用:①轻至中度的呼吸困难,表现为呼吸急促,出现三凹征及鼻翼煽动,皮肤发绀。②动脉血气异常:pH值<7.35,动脉血二氧化碳分压>45 mmHg或动脉血氧分压/吸入氧浓度<250 mmHg。 禁忌证 心跳或呼吸停止;自主呼吸微弱,频繁呼吸暂停;气道分泌物多,咳嗽无力,气道保护能力差,

continuous 英 /kən'tɪnjʊəs/  美 /kən'tɪnjʊəs/

释    义   adj. 连续的,持续的;继续的;连绵不断的

例    句   Most often, patients get a continuous positive airway pressure (CPAP) device, which blows air intothe nose to prevent the throat tissues from sagging shut.  一般来说,患者会拿到一个稳定气道正压装备(CPAP),这个装备用于向鼻孔输入空气以避免喉咙组织下垂。

 

positive 英 /ˈpɒzətɪv/  美 /'pɑzətɪv/

释    义   n. 正数;[摄] 正片      adj. 积极的;[数] 正的,[医][化学] 阳性的;确定的,肯定的

例    句   Explain to interested patients that the standard treatment for sleep apnea is to provide continuouspositive airway pressure, or CPAP, through a mask worn during sleep. 向感兴趣的患者解释睡眠呼吸暂停的标准治疗是在睡眠时通过一个面罩提供持续气道正压通气(CPAP)。  

 

airway 英 /'eəweɪ/  美 /'ɛrwe/

释    义   n. 导气管;空中航线;通风孔

例    句   To analyze the effect of breathing support of nasal continuous positive airwaypressure(NCPAP)in hyaline membrane disease (HMD) of the newborn.  目的 探讨鼻塞式持续气道正压通气 (NCPAP)在新生儿肺透明膜病中的呼吸支持作用及其护理。

 

pressure 英 /'preʃə/  美 /'prɛʃɚ/

释    义   n. 压力;压迫,[物] 压强      vt. 迫使;密封;使……增压

例    句   Comparing UPPP with CPAP(continuous positive airway pressure), PSG changes were larger in CPAP.  与持续鼻腔正压通气比较,UPPP对PSG参数改变更优。

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