Early Acquisition of Pneumocystis jirovecii Colonization and Potential Association With Respiratory Distress Syndrome in Preterm Newborn Infants复制标题

早期获得肺囊虫定植与早产儿呼吸窘迫综合征的关系

Pneumocystis jirovecii is an atypical opportunistic fungus with lung tropism and strong host species specificity, which causes pneumonia in immunosuppressed individuals worldwide. Interstitial plasma cell pneumonia was the first human disease associated with Pneumocystis infection. This disease appeared endemically and in institutional epidemics in Central Europe during the period surrounding World War II, principally involving preterm-born or malnourished infants. Since then Pneumocystis pneumonia (PcP) had only been reported infrequently in patients with malignancies and solid organ transplantations until the Human immunodeficiency virus (HIV) pandemia turned PcP into a major medical and public health problem at the end of the twentieth century.The AIDS epidemic stimulated research on PcP that can be considered just the tip of the iceberg of human Pneumocystis infection.

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