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Renal dysfunction associated with intra-abdominal hypertension and the abdominal compartment syndrome.
与腹内高压和腹腔间隔室综合征相关的肾功能障碍。

摘要

Once considered mostly a postsurgical condition, intra-abdominal hypertension (IAH) and the abdominal compartment syndrome (ACS) are now thought to increase morbidity and mortality in many patients receiving medical or surgical intensive care. Animal data and human observational studies indicate that oliguria and acute kidney injury are early and frequent consequences of IAH/ACS and can be present at relatively low levels of intra-abdominal pressure (IAP). Among medical patients at particular risk are those with septic shock and severe acute pancreatitis, but the adverse effects of IAH may also be seen in cardiorenal and hepatorenal syndromes. Factors predisposing to IAH/ACS include sepsis, large volume fluid resuscitation, polytransfusion, mechanical ventilation with high intrathoracic pressure, and acidosis, among others. Transduction of bladder pressure is the gold standard for measuring intra-abdominal pressure, and several nonsurgical methods can help reduce IAP. The role of renal replacement therapy for volume management is not well defined but may be beneficial in some cases. IAH/ACS is an important possible cause of acute renal failure in critically ill patients and screening may benefit those at increased risk.

译文

腹腔内高压 (IAH) 和腹腔间隔室综合征 (ACS) 曾经被认为主要是一种术后情况,现在被认为增加了许多接受内科或外科重症监护的患者的发病率和死亡率。动物数据和人类观察性研究表明,少尿和急性肾损伤是 IAH/ACS 的早期和频繁后果,并且可以在相对较低的腹内压 (IAP) 水平下出现。处于特殊风险的内科患者包括感染性休克和重症胰腺炎患者,但 IAH 的副作用也可能见于心肾和肝肾综合征。诱发 IAH/ACS 的因素包括败血症、大容量液体复苏、多次输血、高胸内压机械通气和酸中毒等。膀胱压力的传导是测量腹内压力的金标准,几种非手术方法可以帮助减少 IAP。肾脏替代疗法在容量管理中的作用尚未明确,但在某些情况下可能是有益的。IAH/ACS 是重症患者急性肾功能衰竭的一个重要可能原因,筛查可能有益于风险增加的患者。

abdominal compartment syndrome

儿科 腹外器官系统功能损害 疾病
概述  :  

腹腔间室综合症(abdominal compartment syndrome,ACS)是腹腔压力(intra-abdominal pressure,IAP)出现稳定升高并且>20mmHg(伴或不伴有腹腔灌注压(abdominal perfusion pressure,APP)≤60mmHg),同时合并有新的器官功能障碍和衰竭。 病理生理腹腔内高压(intra-abdominal hypertensiou,IAH)发展会造成机体多器官、多系统功能障碍或衰竭。1.心血管紊乱:I

abdominal 英 /æbˈdɒmɪnl/  美 /æbˈdɑːmɪnl/

释    义   adj. 腹部的;有腹鳍的

例    句   Depositions of different time in rats' abdominal skin could be fitted with the two compartmentmodel. 在小鼠皮肤中滞留量的动力学过程符合二室模型。

短    语   abdominal pain  腹痛

abdominal cavity  腹腔

abdominal wall  腹壁


compartment 英 /kəmˈpɑːtmənt/ 美 /kəmˈpɑːrtmənt/

释    义   n. [建] 隔间;区划;卧车上的小客房

vt. 分隔;划分

例    句   Intra-abdominal hypertension (IAH) and Abdominal Compartment Syndrome (ACS) are increasingly considered be important. 腹腔内高压和腹腔间隔室综合征日益受到重视。

短    语   compartment syndrome  筋膜室综合征;间室症候群

passenger compartment  乘客舱;客厢;包房

engine compartment  机舱;发动机室;机器间

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