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首页 > 医学词汇大全 > Tetralogy of Fallot
Tetralogy of Fallot

儿科

关键词儿科 疾病 先天性心脏病

词汇介绍

拓展阅读

解析

tetralogy    英 /tɪ'trælədʒɪ/  美 /te'trælədʒi, tə-/

释    义   n. 四部曲;四联剧

例    句   The percutaneous balloon dilatation of the stenotic right outflow tract is one of the effective palliative therapies for infants with tetralogy of Fallot. 经皮球囊导管扩张狭窄的右心室流出口,是对法洛四联症患儿合并缺氧发作的有效姑息疗法之一。

 

Fallot

释    义   n. (Fallot)人名;(法)法洛

例    句   Cardiac defects included 63 Fallot's Tetralogy, 5 double-outlet of right ventricle, 4 anomalous pulmonary venous and 10 other defects.  病种包括法洛四联症63例,右心室双出口5例,肺静脉畸形引流4例,其他病变10例。

概述

法洛四联症 (TOF)是婴儿期后最常见的青紫型先天性心脏病,约占所有先天性心脏病的12%。法洛四联症由4种畸形组成,右心室流出道梗阻、室间隔缺损、主动脉骑跨、右心室肥厚,此外本病可合并其他心血管畸形,如25%的法洛四联症患儿为右位型主动脉弓;其他如左上腔静脉残留、冠状动脉异常、房间隔缺损、动脉导管未闭、肺动脉瓣缺如等。病理解剖右心室流出道梗:狭窄范围可自右心室漏斗部入口至左、右肺动脉分支。可为漏斗部狭窄、动脉瓣狭窄或两者同时存在。常有肺动脉瓣环、肺动脉总干的发育不良和肺动脉分支的

Echo-Doppler Assessment of Left Filling Pressures in Adults With Repaired Tetralogy of Fallot复制标题

多普勒超声评价成人法洛四联症修复后左侧充盈压

发表时间:2019-08-01

影响因子:5.8

作者: William R. Miranda

期刊:Circ Cardiovasc Imaging

The prevalence of left ventricular (LV) diastolic dysfunction is expected to rise as patients with tetralogy of Fallot (ToF) age. Elevated LV filling pressures by cardiac catheterization carry worse prognosis in this population,1 but data on echo-Doppler assessment of LV diastolic function/filling pressures in adults with ToF are limited. We identified 48 adults (age ≥18 years) with repaired ToF undergoing right heart catheterization and transthoracic echocardiography within 7 days (median, −1 day [−1 to −2]) between June 2004 and December 2018. None had prior mitral valve replacement/repair. Echocardiographic and invasive hemodynamic data were abstracted from the reports. Cardiac catheterization was performed in a fasting state and elevated LV filling pressures defined as pulmonary artery wedge pressure (PAWP) >12 mmHg.2 Data are presented as counts, mean±SD, or medians (25th to 75th percentile). Groups were compared using t test and Wilcoxon test for continuous data and χ2 and Fisher exact tests for nominal variables, whichever appropriate.

译文

随着法洛四联症(tof)患者年龄的增长,左室舒张功能障碍的患病率有望上升。心导管插入术引起的左室充盈压升高对这一人群的预后不利,但超声多普勒评价成人tof左室舒张功能/充盈压的数据有限。我们确定在2004年6月至2018年12月期间的7天内(中位数,-1天[-1至-2])接受右心导管和经胸超声心动图治疗的48名成人(年龄≥18岁)。无一例曾行二尖瓣置换/修复术。从报告中提取超声心动图和有创血流动力学数据。心导管在禁食状态下进行,左室充盈压升高定义为肺动脉楔压(pawp)>12 mmhg。2数据以计数、平均值±标准差或中间值(25%至75%)表示。以t检验和wilcoxon检验作为连续数据,以x2检验和fisher精确检验作为名义变量进行比较。