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Intramural Ventricular Septal Defect Is a Distinct Clinical Entity Associated With Postoperative Morbidity in Children After Repair of Conotruncal Anomalies.
壁内室间隔缺损是一种独特的临床实体,与儿童圆锥动脉干畸形修复后的术后发病率相关。
cardiac surgical procedures congenital heart defects heart septal defects pediatrics ventricular
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摘要

BACKGROUND:Intramural ventricular septal defects (VSDs) are interventricular communications through right ventricular free wall trabeculations that can occur after repair of conotruncal anomalies. We assessed the prevalence of residual intramural VSDs and their effect on postoperative course.
METHODS AND RESULTS:Children who underwent biventricular repair of a conotruncal anomaly from January 1, 2006, to June 30, 2013, and had a postoperative transthoracic echocardiogram were included. Images were reviewed for residual intramural or nonintramural VSDs. The primary outcome was a composite of mortality, extracorporeal membrane oxygenation use, and need for subsequent catheter or surgical VSD closure. The secondary outcome was postoperative hospital length of stay. A residual VSD was present in 256 of the 442 subjects (58%), of which 231 (90%) were 

译文

背景: 壁内室间隔缺损 (VSDs) 是通过右心室游离壁小梁形成的心室间通信,可在圆锥动脉干畸形修复后发生。我们评估了残留壁内 VSDs 的患病率及其对术后病程的影响。
方法和结果: 从 2006年1月1日到 2013年6月30日接受圆锥动脉干畸形双心室修复术并进行术后经胸超声心动图检查的儿童被包括在内。检查图像是否有残留的壁内或非壁内 VSDs。主要结果是死亡率、体外膜肺氧合使用以及后续导管或外科室间隔缺损闭合的需要。次要结果是术后住院时间。在 256 名受试者 (442) 中,58% 存在残留的 VSD,其中 231 (90%)

Ventricular septal defect

儿科 先天性心脏畸形 临床研究术语
概述  :  

室间隔缺损是指室间隔胚胎发育不全,导致室间隔连续性中断,左、右心室形成异常。它是最常见的先天性心脏畸形一,占先天性心脏病的30%,发生率2/1000室间隔缺损可为单发畸形(约50%),也可为心脏复杂畸形的一部分。病理生理小的室间隔缺损左向右分流量小,不易发生肺动脉高压,临床上可长期无症状;中 等和较大的室间隔缺损产生大量的左向右 分流,肺血管阻力轻度增高,右心负荷增 大,临床上可有中等程度的症状;巨大室间隔缺损左向右分流量大,较快形成肺动脉高压,右心室压力升高接近或超过左心 室压力,出现双向

ventricular    英 /ven'trɪkjʊlə/  美 /vɛn'trɪkjəlɚ/

释    义   adj. 心室的;脑室的;膨胀的;腹部的

例    句   The authors emphasize early operation, firm repair of the VSD and ASD primum and restoration of the function of the mitral valve. 强调本病须尽早手术治疗、术中牢固修补VSD和原发孔ASD及恢复二尖瓣功能的重要性。  

 

septal    英 /'sept(ə)l/  美 /'sɛptl/

释    义   adj. 中隔的;氏族的;隔膜的

例    句   Ventricular septal defect(VSD) is one of the most common congenital heart malformations. 室间隔缺损是最常见的先天性心脏病之一。


defect    英 /'diːfekt; dɪ'fekt/  美 /‘dɪfɛkt/

释    义   n. 缺点,缺陷;不足之处     

vi. 变节;叛变

例    句   The study concluded that Fc calculated by correcting the effect of left ventricular outflow on flowconvergence region can more accurately evaluate the shunt severity of ventricular septal defect.该研究表明通过校正左室流出道血流对会聚区的影响计算出的分流率能更准确地评估室间隔缺损的分流程度。

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