Clinically Significant Gains in Skillful Grasp Coordination by an Individual With Tetraplegia Using an Implanted Brain-Computer Interface With Forearm Transcutaneous Muscle Stimulation复制标题

四肢瘫患者使用植入的脑机接口和前臂经皮肌肉刺激在熟练掌握协调方面有临床意义

Generalizability can also refer to the number of grip types that a user can switch between using the same decoder. A limitation of training minimal-class decoders for individual test items is that additional setup time is needed to switch grips, resulting in standardized testing that stretches across days. This can confound effects specific to objects (eg, weight, shape) with time effects (eg, learning) and limit opportunities for reassessing performance over time. It also fails to address user priorities of spontaneity, decreased setup times, and number of functions available per decoder. For this reason, multiclass GRT decoders were implemented that allowed assessment of all objects without retraining. Performance with the multiclass decoder (see fig 5D) was similar to the single-class decoder for some objects (peg, weight, fork, video tape) but not others (can, block). For block and can, the participant required more time to select the appropriate grip decoder-calibration, reducing transfer rate in multiclass conditions compared to simpler 1 to 2 class decoders. The additional selection time for block was likely related to observed overlap in cortical representation with other GRT object or grips.

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