微信扫码关注“小狗文献”

即刻体验更多权益

文献多,下载快,翻译准

首页 > 医学词汇大全 > Sciatica
Sciatica

骨科

关键词骨科 疾病 周围神经疾病

词汇介绍

拓展阅读

解析

Sciatica 英 /saɪ'ætɪkə/  美 /saɪ'ætɪkə/       

释义   n. [内科] 坐骨神经痛

例句   Sciatica is pain, weakness, numbness or tingling that can begin in the lower back and run down even to the toes. 坐骨神经痛是疼痛,乏力,麻木或刺痛,可以开始在腰部和运行下来甚至到了脚趾。

概述

坐骨神经痛是以坐骨神经循行和分布区域的持续性或阵发性疼痛、麻木为主要临床表现的周围神经疾病。由于发病原因及受压部位不同,可分为根性坐骨神经痛和干性坐骨神经痛2种。病因及病理机制坐骨神经是全身最大的外周神经,由腰骶干、S1-3神经组成,起始于腰骶部的脊髓,途经骨盆,并从坐骨大孔穿出,经梨状肌下孔出骨盆到臀部,在臀大肌深面向下行,循行至腘窝以前,分为胫神经和腓总神经,支配小腿及足的全部肌肉以及除隐神经支配区以外的小腿与足的皮肤感觉。坐骨神经痛的发病机制与神经根及其感觉神经节的受压有关,也与局部炎

18F-FDG PET/MRI in Chronic Sciatica: Early Results Revealing Spinal and Nonspinal Abnormalities复制标题

慢性坐骨神经痛的18F-FDG PET/MRI: 早期结果揭示脊柱和非脊柱异常

发表时间:2017-11-02

影响因子:7.4

作者: Cipriano Peter W

期刊:J NUCL MED

18F-FDG PET/MRI is a novel diagnostic approach that can offer metabolic and structural examinations of painful lesions. Compared with separate acquisition with each modality, simultaneous acquisition with PET and MRI can greatly mitigate motion-induced misregistration. This advantage is significant for specifying pain sources because the common sources of sciatic pain, such as a herniated disk, degenerated facet joints, and impinged spinal nerves, are located very close to one another. The high sensitivity of 18F-FDG PET for metabolically hyperactive foci can be used to detect an abnormal increase in metabolism caused by painful inflammation.A recent PET imaging study demonstrated increased 18F-FDG uptake in injured nerves of rats as well as in denervated calf musculature of the affected limb. Unfortunately, the low spatial resolution and lack of tissue contrast of PET limit distinction among multiple possible pathologies for a detected lesion. The high-resolution anatomic views and superior soft-tissue contrast of MRI can help to resolve the anatomic ambiguity of PET. On the other hand, when multiple or subtle structural abnormalities are detected on MRI, the metabolic contrast on PET can highlight the pain-relevant inflammatory changes within the detected lesions.

译文

18F-FDG PET / MRI是一种新型诊断方法,可以提供疼痛病变的代谢和结构检查。与每种模态的单独采集相比,使用PET和MRI同时采集可以极大地减轻运动引起的重合失调。该优点对于指定疼痛源是重要的,因为坐骨神经疼痛的常见来源,例如椎间盘突出,退化的小关节和撞击的脊神经,彼此非常靠近。 18F-FDG PET对代谢过度活跃灶的高灵敏度可用于检测由疼痛性炎症引起的代谢异常增加。最近的PET成像研究表明,大鼠受损神经以及受影响肢体的失神经小腿肌肉组织中18F-FDG摄取增加。不幸的是,PET的低空间分辨率和缺乏组织对比限制了检测到的病变的多种可能病理之间的区别。 MRI的高分辨率解剖学视图和优越的软组织对比度有助于解决PET的解剖学模糊性。另一方面,当在MRI上检测到多个或微妙的结构异常时,PET上的代谢对比可突出检测到的病变内与疼痛相关的炎性变化。