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首页 > 医学词汇大全 > Intermittent claudication
Intermittent claudication

骨科

关键词骨科 疾病 下肢缺血性疾病

词汇介绍

拓展阅读

解析

intermittent   /ɪntə'mɪtənt/   /ˌɪntərˈmɪtənt/      

释义   adj. 间歇的,断断续续的 

例句   It and reversing current different is not to be, but with a anode intermittently stop, because the intermittent power supply current interrupted, cathode potential with time periodically change. 它与换向电流所不同的是不把镀件作阳极,而是间歇地停止供电,由于间歇中断电流,阴极电位随时间周期性地变化。

 

claudication   /,klɔːdɪ'keɪʃ(ə)n/     

释义   n. [] 跛行;跛 

例句   The symptoms of claudication can be mimicked by many other conditions which cause pain in the legs such as arthritis and nerve problems (neuropathy). 许多其它导致腿部疼痛的情形也可能产生跛行症状,例如关节炎和神经疾病(神经病变)。


概述

与定义间歇性跛行是下肢缺血性疾病的一个临床表现,患者从开始走路,或走了一段  路程以后就会出现单侧或双侧腿痛,下肢麻木无力,以至跛行,但休息片刻后,症状可以很快缓解或消失,仍可继续行走,再走一段时间后,上述过程和状态再度出现。病理及病生理基础神经源性间歇性跛行及脊髓源性间歇性跛行在病理基础上有着基本的相同点,与以下几个方面有关,即发育性椎管狭窄,脊柱骨关节病所致的骨质增生,椎板肥厚,小关节肥大,多节段的椎间盘突出,黄韧带肥厚,后纵韧带骨化,强直性脊柱炎后期的脊柱僵直和韧带骨化,脊柱

Supervised Exercise Therapy and Revascularization for Intermittent Claudication: Network Meta-Analysis of Randomized Controlled Trials复制标题

监督运动治疗和血运重建治疗间歇性跛行: 随机对照试验的网络Meta分析

发表时间:2019-02-12

影响因子:9.5

作者: Athanasios Saratzis

期刊:JACC Cardiovasc Interv

Multiple trials have compared the efficacy and effectiveness of SET, PTA, and best medical therapy (BMT) using a plethora of different designs. The vast majority of trials consisted of treatment arms directly comparing therapeutic modality with another. Previous systematic syntheses of published research have suggested that SET may be superior to BMT or early PTA. The most recent meta-analyses have suggested that SET combined with PTA may be the optimal initial treatment strategy. These meta-analyses, however, mostly included studies with head-to-head comparisons between 2 specific treatment arms (e.g., PTA vs. SET) or used an approach that did not allow the inclusion and direct comparison of all potential treatments in the context of IC. Using this approach to perform a synthesis of the available research means that a significant body of evidence may have been overlooked. Furthermore, previous meta-analytic attempts in this area have not included all available QoL assessments in their reporting, because various different tools have been used in claudication trials across the years.

译文

多项试验使用过多的不同设计比较了SET,PTA和最佳药物治疗(BMT)的疗效和有效性。绝大多数试验包括直接将治疗方式与另一种治疗方式进行比较的治疗组。先前系统综合已发表的研究表明,SET可能优于BMT或早期PTA。最近的荟萃分析表明,SET结合PTA可能是最佳的初始治疗策略。然而,这些荟萃分析主要包括2个特定治疗组之间的头对头比较研究(例如,PTA与SET)或使用的方法不允许包含和直接比较所有可能的治疗方法。 IC使用这种方法对现有研究进行综合,意味着可能忽略了大量证据。此外,之前在该领域的荟萃分析尝试并未将所有可用的QoL评估纳入其报告中,因为多年来在跛行试验中使用了各种不同的工具。