微信扫码关注“小狗文献”

即刻体验更多权益

文献多,下载快,翻译准

首页 > 医学词汇大全 > Cervical spondylosis
Cervical spondylosis

骨科

关键词骨科 疾病 慢性退行性疾病

词汇介绍

拓展阅读

解析

Cervical 英 /'sɜːvɪk(ə)l; sɜː'vaɪk(ə)l/  美 /'sɝvɪkl/ 

释义   adj. 颈的;子宫颈的 

例句   This is why it is very important for women to have regular cervical smear test. 这就是为什么这是非常重要的妇女有定期子宫颈抹片检查。

 

Spondylosis /spɒndɪˈləʊsɪs/

释义   n. 椎关节强硬 

例句   Now, the inner fixation and minimal invasive skills are popular in the treatment of the spondylosis. 目前内固定技术和微创技术已经成为手术治疗颈椎病的趋势。


概述

颈椎病是颈椎间盘组织退行性改变及其继发性病变后累及颈部神经根、脊髓、椎动脉或交感神经并出现相应临床表现者。颈椎病是国内约定俗成的一个术语,其定义是因颈椎间盘退变本身及其继发性改变刺激或压迫邻近组织,并引起各种症状和/或体征。颈椎病现代的基本概念,是以颈椎间盘退变为主要病变基础,包括颈周围肌肉、关节继发性改变和相邻椎体退变增生直到压迫神经血管等,并诱发与之相关临床症状和体征。尽管这个概念范畴基本表述了颈椎病的病理和临床的特征,但这一名称由于不能很好地反映颈椎生物力学和脊髓功能,目前也有争论。病

MRI evidence of brain atrophy, white matter damage, and functional adaptive changes in patients with cervical spondylosis and prolonged spinal cord compression复制标题

颈椎病和脊髓长时间压迫患者脑萎缩、脑白质损伤和功能适应性改变的MRI证据

发表时间:2019-06-26

影响因子:4.0

作者: Ángela Bernabéu-Sanz

期刊:Eur Radiol

Cervical spondylosis (CS) is a chronic degenerative disease present in the majority of people after the fifth decade of life. Frequently found in asymptomatic adults, it may progress to spinal cord compression and cervical spondylotic myelopathy (CSM). The evolution from CS to CSM is highly variable and difficult to predict, with patients experiencing a rather benign form of the disease while others experiencing substantial deterioration over time. Generally, the treatment for mild and moderate disease is conservative, with surgical intervention advised for patients with severe intractable pain, progressive disease, or associated neurological deficits. Yet, in some patients with mild or moderate disease, the absence of pain and the imprecision of the clinical manifestations could mask the development of a severe CSM.Despite the potential irreversible neurological deficits of CS, its pathophysiology is still poorly understood. The majority of the studies have been focused on the spinal cord overlooking its connection with the cortex, with few studies analyzing the effects of CSM in the brain, suggesting that CSM can lead to neuronal damage distal to the spinal lesion and functional reorganization of the sensorimotor cortex that could be relevant for postsurgical recovery.

译文

颈椎病(CS)是一种慢性退行性疾病,存在于大多数人生命的第五个十年之后。在无症状的成人中经常发现,它可能发展为脊髓压迫和脊髓型颈椎病(CSM)。从CS到CSM的演变变化很大且难以预测,患者经历了相当良性的疾病形式,而其他患者随着时间的推移经历了严重的恶化。一般来说,轻度和中度疾病的治疗是保守的,建议对患有严重顽固性疼痛,进行性疾病或相关神经功能缺损的患者进行手术干预。然而,在一些患有轻度或中度疾病的患者中,没有疼痛和临床表现的不精确可能掩盖了严重CSM的发展。尽管CS具有潜在的不可逆的神经缺陷,但其病理生理学仍然知之甚少。大多数研究都集中在脊髓上,忽略了与皮层的关系,很少有研究分析CSM对大脑的影响,提示CSM可导致脊柱病变远端的神经元损伤和感觉运动的功能重组。皮质可能与术后恢复有关。