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首页 > 医学词汇大全 > Knee Arthritis
Knee Arthritis

骨科

关键词骨科 临床研究术语 骨关节病

词汇介绍

拓展阅读

解析

Arthritis 英 /ɑː'θraɪtɪs/ 美 /ɑr'θraɪtɪs/

释义   n. [外科] 关节炎

例句   You should have a diagnosis by your doctor as soon as possible if you suspect you have arthritis.

你应该有一个诊断您的医生尽快如果您怀疑自己有关节炎。

概述

一、疾病概述或定义 膝骨关节炎(osteoarthritis,OA)是一种退行性关节疾病,又称增生性关节炎、退行性关节炎或骨关节病,是由于滑膜关节的退变引起的以关节疼痛、僵硬和活动受限为特征的关节病变。OA可分为原发性OA和继发性OA。前者确切病因不清,可能与年龄、性别、职业、种族、肥胖、遗传和过度运动等因素有关;后者可继发于任何关节损伤或疾病,如半月板损伤。 二、病因及临床意义 OA的发病率高,尤其在中老年人群中是一种常见病、多发病,女性比男性多见。症状轻者表现为

The effect of rheumatoid arthritis on patient-reported outcomes following knee and hip replacement: evidence from routinely collected data复制标题

类风湿关节炎对膝关节和髋关节置换后患者报告结局的影响: 来自常规收集数据的证据

发表时间:2019-06-01

影响因子:5.1

作者: Burn E

期刊:Rheumatology (Oxford)

Whether individuals with RA achieve equivalent gains from undergoing TKR and THR as those with OA is not yet known. Given multiple joint involvement, systemic comorbidity and polypharmacy, it is plausible that outcomes for individuals with RA may be worse than for those with OA. Moreover, as it is recommended that hip replacement should generally precede knee replacement for those with RA, the relationship between RA and outcomes could differ depending on the procedure. The success of TKR and THR have traditionally been measured by implant survival. There is, however, an increased awareness that patient-reported outcome measures (PROMs) provide a more appropriate indicator of effectiveness and are more closely tied to the reasons for performing surgery. The Oxford Knee Score (OKS) and Oxford Hip Score (OHS) are joint-specific PROMs for knee and hip replacement, respectively, with questions on both pain and function. Meanwhile, the EuroQol 5-dimension 3-level (EQ-5D-3L) questionnaire measures overall health-related quality of life.

译文

RA患者是否通过TKR和THR获得与OA患者相当的收益尚不清楚。鉴于多种关节受累,系统性合并症和多种药物治疗,RA患者的预后可能比OA患者的预后更差。此外,由于建议髋关节置换术通常应在RA患者膝关节置换术之前进行,因此RA与结果之间的关系可能因手术而异。TKR和THR的成功传统上通过种植体存活来衡量。然而,人们越来越意识到患者报告的结果指标(PROM)提供了更合适的有效指标,并且与进行手术的原因更为紧密相关。牛津膝关节评分(OKS)和牛津髋关节评分(OHS)分别是膝关节和髋关节置换的联合特异性PROM,对疼痛和功能都有疑问。同时,EuroQol 5维3级(EQ-5D-3L)调查问卷测量整体健康相关的生活质量。