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首页 > 医学词汇大全 > Angioplasty
Angioplasty

骨科

关键词骨科 治疗方法 微创手术

词汇介绍

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解析

Angioplasty /,ændʒɪo'plæsti/

释义   n. 血管成形术

复数 angioplasties

例句   About half of the patients were treated with thrombolytic therapy and half underwent angioplasty.

约有半数的病人行溶栓治疗,半数病人行血管成形术。

概述

一、手术概述或定义血管成形术是一个医学上的专业名词,它的含义是用一种方法使狭窄的血管恢复它原来的形状,使血流重新畅通,供血恢复接近正常。又称为球囊血管成形术。 二、手术方式沿革这一疗法源于上世纪60年代,上世纪80年代前主要采用球囊导管进行治疗,所以成形术又称为球囊血管成形术,经皮经腔冠状动脉血管成形术(PTCA)和冠状2动脉球囊扩张术。血管成形术是微创手术,它通过上肢或下肢的一个小切口抵达病变的动脉。然后医生通过切口插入一个小的可扩张球囊,通过球囊的物理性扩张以及排除狭窄的或被阻塞的

Pretreatment with P2Y12 receptor antagonists in ST-elevation myocardial infarction: a report from the Swedish Coronary Angiography and Angioplasty Registry复制标题

P2Y12受体拮抗剂预处理ST段抬高型心肌梗死: 瑞典冠状动脉造影和血管成形术登记研究报告

发表时间:2019-04-14

影响因子:23.2

作者: Redfors B

期刊:Eur Heart J

Potential complications of STEMI that are associated with a considerable risk of dying include stent thrombosis, IRA occlusion, and cardiogenic shock. Therefore, the absence of an association between pretreatment with P2Y12 receptor antagonists and these events in our study is consistent with the lack of association between pretreatment and 30-daymortality. An occluded IRA at the time of primary PCI increases the risk of dying after STEMI and was an independent predictor of all-cause death in the present study. Recognition of the prognostic importance of IRA patency led to a recommendation that P2Y12 antagonists be administered at first medical contact. However, in the ATLANTIC trial, prehospital administration of ticagrelor was not superior to inhospital administration in regards to either of the two co-primary endpoints: preprocedure resolution of ST-segment elevation and TIMI flow Grade 3 in the IRA. Thus, neither the ATLANTIC trial nor our study—the largest cohort study so far conducted—showed any beneficial effect of pretreatment with P2Y12 receptor antagonists on IRA patency.

译文

与死亡风险相关的STEMI的潜在并发症包括支架血栓形成,IRA闭塞和心源性休克。因此,在我们的研究中,用P2Y12受体拮抗剂预处理与这些事件之间没有关联,这与预处理和30天死亡之间缺乏关联是一致的。在直接PCI时闭塞的IRA增加了STEMI后死亡的风险,并且是本研究中全因死亡的独立预测因子。认识到IRA通畅的预后重要性导致建议P2Y12拮抗剂在首次医学接触时给药。然而,在ATLANTIC试验中,对于两个共同主要终点中的任一个,院前给予替卡格雷并不优于院内给药:术前ST段抬高的分辨率和IRA中的TIMI流量等级3。因此,ATLANTIC试验和我们的研究 - 迄今为止进行的最大的队列研究 - 均未显示用P2Y12受体拮抗剂预处理对IRA通畅的任何有益效果。