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fibromyalgia

骨科

关键词骨科 临床研究术语 临床疾病

词汇介绍

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解析

Fibromyalgia /,faibrəumai'ældʒi:ə/ 

释义   n. 纤维肌痛;纤维组织肌痛

例句   While fibromyalgia is a chronic condition, it does not damage the joints, muscles, or internal organs.

虽然纤维肌痛是一种慢性疾病,但它不会损伤关节、肌肉或内脏器官。

概述

一、疾病概述或定义纤维肌痛综合征,也称纤维肌痛症,是以全身弥漫性疼痛为主要特征的疾病,严重影响患者的身心健康。男女比例约为1:7,欧美国家患病率为 2%~8%,我国香港地区约为1%,大陆和台湾地区尚缺乏流行病学报道。有研究发现,随年龄增长,本病患病率也随之越高,50~60岁女性中患病率高达8%。发病机制方面,目前仍然不清,主流观点认为“中枢敏化”是本病的主要发病机制。 二、疾病沿革西方医学界对本病的认知经历了400余年的漫长过程。最早在1592年就出现了对本病的描述,当时被称为肌肉风湿

Secondary Fibromyalgia复制标题

继发性纤维肌痛

发表时间:2019-02-19

影响因子:3.2

作者: Bennett R M

期刊:J Rheumatol

The concept of secondary fibromyalgia (FM) has garnered increasing interest over the last decade. This has resulted from the realization that many common rheumatic disorders have an FM comorbidity that influences, or should influence, optimal management. In this edition of The Journal, Wolfe and colleagues reconsider the issue of primary and secondary FM, asking whether they are equivalent. Currently, there is no universally agreed-upon definition. Dr. Kahler Hench, the originator of the term fibromyalgia, provided this definition: Fibrositis is considered primary when there is no associated underlying disorder and secondary when it occurs in patients with underlying rheumatic or other organic disease”. The 1990 American College of Rheumatology (ACR) criteria paper noted: “To avoid argument over the existence or nonexistence of ‘secondary fibromyalgia,’ which is believed by some investigators to be fibromyalgia caused [author’s italics] by another condition, we adopted the term secondary-concomitant fibromyalgia [original italics] to indicate fibromyalgia occurring in the presence of another significant rheumatic disorder which may have been caused by or was merely associated with the patient’s fibromyalgia”. In the current paper by Wolfe, et al, the following definition is given: Secondary FM is FM occurring in the presence of another clinically important and dominant medical disorder. We agree with this simplified definition and note that there is an ever-increasing list of disorders that have been associated with FM [Table 1; plus the same table with references (Supplementary Table 1, available with the online version of this article)]; whether a patient is designated as having primary FM becomes dependent upon a diligent search for all such associated comorbidities.

译文

继发性纤维肌痛(FM)的概念在过去十年中引起了越来越多的关注。这是由于认识到许多常见的风湿性疾病具有影响或应该影响最佳管理的FM共病。在本期“华尔街日报”中,Wolfe及其同事重新考虑了主要和次要调频问题,并询问它们是否相同。目前,没有普遍认同的定义。 Kahler Hench博士是纤维肌痛这一术语的创始人,他提供了这样的定义:当没有相关的潜在疾病时,纤维炎被认为是原发性疾病,当患有潜在的风湿性或其他器质性疾病的患者发生时,纤维炎被认为是次要的。 1990年美国风湿病学会(ACR)标准文件指出:“为避免争论'继发性纤维肌痛的存在或不存在',一些研究者认为纤维肌痛是由另一种情况造成的[作者斜体],我们采用了这个术语继发性伴随的纤维肌痛[原始斜体]表示在存在另一种可能由患者的纤维肌痛引起或仅与其相关的显着风湿性疾病的情况下发生的纤维肌痛“。在Wolfe等人的当前论文中,给出以下定义:次级FM是在另一种临床上重要的和显性的医学病症存在下发生的FM。我们同意这个简化的定义,并注意到与FM相关的疾病列表越来越多[表1;加上与引用相同的表(补充表1,可在本文的在线版本中获得)];患者是否被指定为患有原发性FM变得依赖于对所有此类相关合并症的勤奋搜索。