To investigate mechanisms of vascular morphogenesis in tissue repair, we performed ovariectomy with resection of the corresponding branches of the ovarian vessels in nude mice. This induces a vascular network remodeling response in the healing ovarian pedicle. Reconstruction of 2000 histological serial sections demonstrated that a new vascular network composed of venous-venous loops forms in the wall of the dilated ovarian vein. Preexisting veins of all sizes, including a branch of the main artery, are subjected to segmentation. Loop formation and segmentation are based on intussusceptive microvascular growth. Loop formation is followed by elongation. Loop remodeling occurs also by intussusception and results in the formation of compound loop systems. All loop systems observed were completely patent. Blind-ending sprouts were extremely rare. Anastomoses between the preexisting vessels subjected to segmentation and the loop systems were established to include the newly formed vessels into the preexisting vascular network. The formation of an increasing number of patent loop systems likely decreases hypoxia and subsequently arrests angiogenesis with transformation of the granulation tissue into a scar. Loop formation also occurred inside a large thrombus that occluded a part of the lumen of the main vein.
Vascular morphogenesis and remodeling in a model of tissue repair: blood vessel formation and growth in the ovarian pedicle after ovariectomy.
椎弓根起于椎体后部，向后方突起，椎弓根外形呈弧形，并且与椎体、关节突和椎板融合在一起。 临床意义 近20年来，经椎弓根螺钉固定技术广泛用于腰椎管狭窄等脊柱外科手术中，不同文献报道的置钉误置率差别很大，这就要求外科医生对腰椎椎弓根的解剖有较为全面的认识，否则会出现严重手术相关并发症。 椎弓根螺钉与椎弓根 椎弓根螺钉置钉过深容易损伤腹腔血管等组织。有学者研究在30套成人干燥腰椎标本上测量了
pedicle 英 /'pedɪk(ə)l/ 美 /'pɛdəkl/
释义 n. 蒂；[动] 肉茎；花梗；椎弓根
例句 In addition, pedicle screw constructs appear to have a better ability to correct scoliosis in comparison with hooks and hybrid constructs. 此外，与经钉钩固定和混合结构方式相比，椎弓根螺钉方式在纠正脊柱侧凸上有更好的优势。